Clinical Treatment and Nursing Care of Gastrointestinal Stromal Tumor Acute Abdomen

医学 主旨 急腹症 穿孔 围手术期 间质瘤 外科 腹膜炎 甲磺酸伊马替尼 护理 腹部 普通外科 伊马替尼 内科学 护理部 间质细胞 髓系白血病 材料科学 冲孔 冶金
作者
Luyin Han,Chaoyong Shen,Yongming Tian
出处
期刊:Journal of gastroenterology and hepatology research [ACT Publishing Group]
卷期号:4 (11): 1821-1825 被引量:1
标识
DOI:10.17554/j.issn.2224-3992.2015.04.548
摘要

Aims: Recently, the further understanding of gastrointestinal stromal tumor (GIST) and development of diagnosis and treatment methods have led to an increase in diagnosed cases. Patients may present with acute abdomen, perforation or peritonitis, and acute intestinal obstruction. This work aims to investigate the clinical treatment and nursing methods of GIST patients with an acute abdomen symptom. Methods: A retrospective analysis was conducted for the treatment and nursing care of 45 GIST cases, in which the primary symptom was acute abdomen. The patients were admitted at the General Surgery of Sichuan University from January 2008 to January 2011. Results: A total of 45 GIST patients (28 males and 17 females) were involved in the research, which included 29 stomach tumor cases (64.4%), 11 small intestine-related cases (24.5%), 3 colon-related cases (6.7%), and 2 rectum-related cases (4.4%). Among these cases, 11 were diagnosed with acute intestinal obstruction (24.5%), 27 with acute gastrointestinal hemorrhage (60.0%), and 7 with abdominal hemorrhage caused by tumor rupture (15.5%); 41 cases underwent surgical treatment, improved after perioperative care, and were subsequently discharged from the hospital; another 4 cases with advanced tumors were treated with oral imatinib mesylate as neoadjuvant therapy, which eventually led to a partial relief. Conclusions: No clinical specificity regarding GIST exists. Thus, GIST is prone to misdiagnosis and/or missed diagnosis. Early diagnosis and treatment increase the prognosis of patients. The integrity of the treatment and nursing care can effectively and safely help patients during the perioperative period.

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