亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Associations between blood and urinary manganese with metabolic syndrome and its components: Cross-sectional analysis of National Health and Nutrition Examination Survey 2011–2016

腰围 全国健康与营养检查调查 医学 优势比 代谢综合征 置信区间 内科学 横断面研究 泌尿系统 血脂异常 内分泌学 生理学 环境卫生 体质指数 肥胖 人口 病理
作者
Kenneth Lo,Jing Yang,Chaolei Chen,Lin Liu,Yuqing Huang,Yingqing Feng,Ai-Min Yang
出处
期刊:Science of The Total Environment [Elsevier BV]
卷期号:780: 146527-146527 被引量:28
标识
DOI:10.1016/j.scitotenv.2021.146527
摘要

Manganese (Mn) may improve cardiometabolic health with its anti-oxidative ability. However, epidemiological evidence on the overall and sex-specific relationship between Mn exposure and metabolic syndrome (MetS) has been inconclusive. We evaluated the associations of urinary (n = 1713) and blood (n = 3335) Mn levels with the prevalence of MetS, its components (elevated waist circumference, impaired glucose metabolism, elevated blood pressure and dyslipidemia) and sex-dependent heterogeneities among participants in the United States National Health and Nutrition Examination Survey 2011–2016. After adjusting for multiple covariates and the levels of other metals (Arsenic, Barium, Cadmium, Mercury, Molybdenum, Tin and Uranium), urinary Mn at the third quartile associated with a lower odd of MetS (odds ratio [OR] = 0.55, 95% confidence interval [C.I.] = 0.32–0.97), elevated waist circumference (OR = 0.56, 95% C.I. = 0.36–0.86) and elevated fasting plasma glucose (OR = 0.46, 95% C.I. = 0.27–0.76) among overall participants, and lower odds of MetS (OR = 0.40, 95% C.I. = 0.16–0.99), elevated waist circumference (OR = 0.39, 95% C.I. = 0.19–0.81) and elevated fasting plasma glucose (OR = 0.44, 95% C.I. = 0.22–0.90) among men. The U-shaped dose-response relationship between urinary Mn and MetS (P non-linear = 0.008) was observed among all participants. We did not observe the significant associations of blood Mn with the prevalence of MetS. Compared with other metals, urinary Mn played a less important role in development of MetS (posterior inclusion probabilities [PIP] = 0.49 for Mn versus 0.54 to 0.91 for other metals), but the contribution of blood Mn (PIP = 0.59 versus 0.60 to 0.61) was similar to other blood metals (Cadmium, Lead, Mercury and Selenium). These findings have provided new evidence of the potential roles of Mn in cardiometabolic health, and the needs to explore how Mn interacts with multiple metals in sex-specific manner.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
3秒前
26秒前
34秒前
科研通AI5应助晚晚采纳,获得10
39秒前
jianghs发布了新的文献求助30
39秒前
袁钰琳完成签到 ,获得积分10
51秒前
55秒前
58秒前
晚晚完成签到,获得积分10
58秒前
晚晚发布了新的文献求助10
1分钟前
1分钟前
僦是卜够完成签到 ,获得积分10
1分钟前
徐悦月关注了科研通微信公众号
1分钟前
1分钟前
1分钟前
徐悦月发布了新的文献求助10
1分钟前
王志鹏发布了新的文献求助10
1分钟前
1分钟前
青木香发布了新的文献求助10
1分钟前
怡然的绮烟完成签到 ,获得积分10
2分钟前
青木香完成签到,获得积分10
2分钟前
Hello应助怡然的绮烟采纳,获得10
2分钟前
2分钟前
nolan完成签到 ,获得积分10
2分钟前
小蘑菇应助科研通管家采纳,获得10
2分钟前
kk完成签到 ,获得积分10
2分钟前
2分钟前
Elvira完成签到,获得积分10
2分钟前
先玩了玉发布了新的文献求助10
2分钟前
笨笨完成签到,获得积分10
3分钟前
vchen0621完成签到,获得积分0
3分钟前
certe完成签到,获得积分10
3分钟前
3分钟前
vchen0621发布了新的文献求助10
3分钟前
先玩了玉完成签到,获得积分10
3分钟前
俞无声完成签到 ,获得积分10
3分钟前
花凉发布了新的文献求助20
4分钟前
科研通AI2S应助科研通管家采纳,获得10
4分钟前
科研通AI2S应助科研通管家采纳,获得10
4分钟前
研友_VZG7GZ应助科研通管家采纳,获得10
4分钟前
高分求助中
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3990031
求助须知:如何正确求助?哪些是违规求助? 3532108
关于积分的说明 11256334
捐赠科研通 3270943
什么是DOI,文献DOI怎么找? 1805146
邀请新用户注册赠送积分活动 882270
科研通“疑难数据库(出版商)”最低求助积分说明 809228