Role of MicroRNAs in Stroke Pathology and Recovery

Ischemic stroke is a leading cause of morbidity and mortality all over the world. Stem cell-based therapies have become a popular choice with scientists and healthcare providers because they could help stroke patients. The fact that several clinical studies have shown that a lack of effective neurorestorative approaches is a barrier to stem cell therapy success and should be addressed. MicroRNA (miRNA) are small non-coding RNA molecules that suppress gene expression, and have emerged as novel therapeutic targets in stroke. In this chapter, we discuss the role of microRNAs in stroke recovery, as well as how they are regulated and how they affect recovery. The use of microRNAs (miRNAs) as a therapeutic agent to protect against stroke pathology is also presented and discussed in this article.