医学
结直肠癌
内科学
循环肿瘤DNA
佐剂
肿瘤科
化疗
阶段（地层学）
辅助化疗
辅助治疗
癌症
生物
古生物学
乳腺癌
作者
Jeanne Tie,Joshua D. Cohen,Kamel Lahouel,Serigne Lo,Yuxuan Wang,Suzanne Kosmider,Rachel Wong,Jeremy Shapiro,Margaret Lee,Sam Harris,Adnan Khattak,Matthew Burge,Marion Harris,James Lynam,Louise Nott,Fiona Day,Theresa Hayes,Sue‐Anne McLachlan,Belinda Lee,Janine Ptak
标识
DOI：10.1056/nejmoa2200075
摘要
The role of adjuvant chemotherapy in stage II colon cancer continues to be debated. The presence of circulating tumor DNA (ctDNA) after surgery predicts very poor recurrence-free survival, whereas its absence predicts a low risk of recurrence. The benefit of adjuvant chemotherapy for ctDNA-positive patients is not well understood.
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