Long‐term results of a short‐term home‐based pre‐ and postoperative exercise intervention on physical recovery after colorectal cancer surgery (PHYSSURG‐C): a randomized clinical trial

医学 随机对照试验 结直肠癌 物理疗法 结直肠外科 优势比 放射治疗 直肠 临床试验 外科 癌症 内科学 腹部外科
作者
Aron Onerup,Ying Li,Kevin Afshari,Eva Angenete,Hanna de la Croix,Carolina Ehrencrona,Anette Wedin,Eva Haglind
出处
期刊:Colorectal Disease [Wiley]
卷期号:26 (3): 545-553 被引量:3
标识
DOI:10.1111/codi.16860
摘要

Abstract Aim The aim of this work was to assess the effect of a short‐term, home‐based exercise intervention before and after colorectal cancer surgery on 12‐month physical recovery within a previously reported randomized control trial (RCT). Method PHYSSURG‐C is an RCT in six participating hospitals in Sweden. Patients aged ≥20 years planned for elective colorectal cancer surgery were eligible. The intervention consisted of unsupervised moderate‐intensity physical activity 2 weeks preoperatively and 4 weeks postoperatively. Usual care was control. The primary outcome measure in PHYSSURG‐C was self‐assessed physical recovery 4 weeks postoperatively. The predefined long‐term follow‐up outcomes included: self‐assessed physical recovery 12 months postoperatively and reoperations and readmissions 91–365 days postoperatively. The statistical models were adjusted with tumour site (colon or rectum), neoadjuvant therapy (none, radiotherapy or chemo/radiotherapy) and type of surgery (open or laparoscopic). Results A total of 616 participants were available for the 12‐month follow‐up. Groups were balanced at baseline regarding demographic and treatment variables. There was no effect from the intervention on self‐reported physical recovery [adjusted odds ratio (OR) 0.91, p = 0.60], the risk of reoperation (OR 0.97, p = 0.91) or readmission (OR 0.88, p = 0.58). Conclusion The pre‐ and postoperative unsupervised moderate‐intensity exercise intervention had no effect on long‐term physical recovery after elective colorectal cancer surgery. There is still not enough evidence to support clinical guidelines on preoperative exercise to improve outcome after colorectal cancer surgery.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
cindywu关注了科研通微信公众号
刚刚
蔡翌文发布了新的文献求助10
刚刚
scabbard24发布了新的文献求助10
刚刚
orixero应助大大的西瓜采纳,获得10
1秒前
1秒前
2秒前
weijie完成签到,获得积分10
2秒前
爆米花应助obdixp采纳,获得20
3秒前
3秒前
小王发布了新的文献求助10
4秒前
6秒前
可靠的如之完成签到,获得积分10
7秒前
专注棒棒糖完成签到 ,获得积分10
7秒前
7秒前
Lily发布了新的文献求助10
7秒前
8秒前
YZQ发布了新的文献求助10
9秒前
黑咖啡完成签到,获得积分10
9秒前
Liufgui应助可靠的如之采纳,获得10
11秒前
科研通AI2S应助阿俊采纳,获得10
12秒前
13秒前
15秒前
17秒前
17秒前
JamesPei应助YZQ采纳,获得10
18秒前
Orange应助邪恶花生米采纳,获得10
18秒前
weijie发布了新的文献求助10
18秒前
hf完成签到,获得积分10
18秒前
18秒前
20秒前
量子星尘发布了新的文献求助30
21秒前
硅负极完成签到,获得积分10
21秒前
zzt发布了新的文献求助10
21秒前
22秒前
Dr.Yang发布了新的文献求助10
23秒前
25秒前
刻苦的秋柔完成签到,获得积分10
27秒前
意大利种马完成签到,获得积分20
28秒前
orixero应助写得出发的中采纳,获得10
30秒前
刘雨森完成签到 ,获得积分10
31秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3988920
求助须知:如何正确求助?哪些是违规求助? 3531290
关于积分的说明 11253247
捐赠科研通 3269903
什么是DOI,文献DOI怎么找? 1804830
邀请新用户注册赠送积分活动 882027
科研通“疑难数据库(出版商)”最低求助积分说明 809052