医学
心力衰竭
疾病
重症监护医学
干预(咨询)
高血压性心脏病
病理生理学
生物信息学
神经科学
心脏病学
内科学
精神科
心理学
生物
作者
Xuewei Huang,Lizhi Hu,Zhuojun Long,Xinyao Wang,Junru Wu,Jingjing Cai
标识
DOI:10.31083/j.rcm2503093
摘要
Hypertensive heart disease (HHD) presents a substantial global health burden, spanning a spectrum from subtle cardiac functional alterations to overt heart failure. In this comprehensive review, we delved into the intricate pathophysiological mechanisms governing the onset and progression of HHD. We emphasized the significant role of neurohormonal activation, inflammation, and metabolic remodeling in HHD pathogenesis, offering insights into promising therapeutic avenues. Additionally, this review provided an overview of contemporary imaging diagnostic tools for precise HHD severity assessment. We discussed in detail the current potential treatments for HHD, including pharmacologic, lifestyle, and intervention devices. This review aimed to underscore the global importance of HHD and foster a deeper understanding of its pathophysiology, ultimately contributing to improved public health outcomes.
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