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The impact of air pollution on atopic dermatitis: A transethnic Mendelian randomization study

医学 全基因组关联研究 生命银行 孟德尔随机化 特应性皮炎 流行病学 家庭医学 环境卫生 皮肤病科 单核苷酸多态性 生物信息学 遗传学 病理 遗传变异 基因型 基因 生物
作者
Yao Ni,Ao He,Janzhou Ye,Wenliang Lv
出处
期刊:Journal of The European Academy of Dermatology and Venereology [Wiley]
被引量:5
标识
DOI:10.1111/jdv.19675
摘要

Journal of the European Academy of Dermatology and VenereologyEarly View LETTER TO THE EDITOR The impact of air pollution on atopic dermatitis: A transethnic Mendelian randomization study Yao Ni, Yao Ni orcid.org/0000-0002-4203-2284 Department of Dermatovenereology, Chengdu Second People's Hospital, Chengdu, China Nanjing University of Traditional Chinese Medicine, Nanjing, ChinaSearch for more papers by this authorAo He, Ao He orcid.org/0009-0002-9872-4412 Department of Plastic Surgery, Affiliated Calmette Hospital of Kunming Medical University, Kunming, ChinaSearch for more papers by this authorJanzhou Ye, Corresponding Author Janzhou Ye [email protected] orcid.org/0000-0002-9205-4609 Department of Dermatovenereology, Yunnan Provincial Hospital of Traditional Chinese Medicine, Kunming, China Correspondence Janzhou Ye, Department of Dermatovenereology, Yunnan Provincial Hospital of Traditional Chinese Medicine, Kunming 650000, China. Email: [email protected] Wenliang Lv, Department of Infection, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100000, China. Email: [email protected]Search for more papers by this authorWenliang Lv, Corresponding Author Wenliang Lv [email protected] Department of Infection, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China Correspondence Janzhou Ye, Department of Dermatovenereology, Yunnan Provincial Hospital of Traditional Chinese Medicine, Kunming 650000, China. Email: [email protected] Wenliang Lv, Department of Infection, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100000, China. Email: [email protected]Search for more papers by this author Yao Ni, Yao Ni orcid.org/0000-0002-4203-2284 Department of Dermatovenereology, Chengdu Second People's Hospital, Chengdu, China Nanjing University of Traditional Chinese Medicine, Nanjing, ChinaSearch for more papers by this authorAo He, Ao He orcid.org/0009-0002-9872-4412 Department of Plastic Surgery, Affiliated Calmette Hospital of Kunming Medical University, Kunming, ChinaSearch for more papers by this authorJanzhou Ye, Corresponding Author Janzhou Ye [email protected] orcid.org/0000-0002-9205-4609 Department of Dermatovenereology, Yunnan Provincial Hospital of Traditional Chinese Medicine, Kunming, China Correspondence Janzhou Ye, Department of Dermatovenereology, Yunnan Provincial Hospital of Traditional Chinese Medicine, Kunming 650000, China. Email: [email protected] Wenliang Lv, Department of Infection, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100000, China. Email: [email protected]Search for more papers by this authorWenliang Lv, Corresponding Author Wenliang Lv [email protected] Department of Infection, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China Correspondence Janzhou Ye, Department of Dermatovenereology, Yunnan Provincial Hospital of Traditional Chinese Medicine, Kunming 650000, China. Email: [email protected] Wenliang Lv, Department of Infection, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100000, China. Email: [email protected]Search for more papers by this author First published: 13 December 2023 https://doi.org/10.1111/jdv.19675 Yao Ni and Ao He share the first authorship. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Open Research DATA AVAILABILITY STATEMENT The data that support the findings of this study are openly available in IEU OpenGWAS (https://gwas.mrcieu.ac.uk/datasets/), the EArly Genetics & Lifecourse Epidemiology (EAGLE) eczema consortium (https://www.ebi.ac.uk/gwas/publications/26482879) and the Japanese Biobank (https://gwas.mrcieu.ac.uk/datasets/bbj-a-90/). ETHICS STATEMENT This study was solely based on publicly accessible deidentified data from published studies and summary database. No separate ethical approval was needed in this study. REFERENCES 1Park SK, Kim JS, Seo HM. Exposure to air pollution and incidence of atopic dermatitis in the general population: a national population-based retrospective cohort study. J Am Acad Dermatol. 2022; 87(6): 1321–1327. 10.1016/j.jaad.2021.05.061 CASPubMedWeb of Science®Google Scholar 2Paternoster L, Standl M, Waage J, Baurecht H, Hotze M, Strachan DP, et al. Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis. Nat Genet. 2015; 47(12): 1449–1456. 10.1038/ng.3424 CASPubMedWeb of Science®Google Scholar 3Palmer TM, Lawlor DA, Harbord RM, Sheehan NA, Tobias JH, Timpson NJ, et al. Using multiple genetic variants as instrumental variables for modifiable risk factors. Stat Methods Med Res. 2012; 21(3): 223–242. 10.1177/0962280210394459 PubMedWeb of Science®Google Scholar 4Carrascosa JM, Morillas-Lahuerta V. Comorbidities in atopic dermatitis: an update and review of controversies. Actas Dermosifiliogr (Engl Ed). 2020; 111(6): 481–486. 10.1016/j.ad.2020.04.009 CASPubMedGoogle Scholar 5Eigenmann PA, Sicherer SH, Borkowski TA, Cohen BA, Sampson HA. Prevalence of IgE-mediated food allergy among children with atopic dermatitis. Pediatrics. 1998; 101(3): E8. 10.1542/peds.101.3.e8 CASPubMedWeb of Science®Google Scholar 6Kantor R, Kim A, Thyssen JP, Silverberg JI. Association of atopic dermatitis with smoking: a systematic review and meta-analysis. J Am Acad Dermatol. 2016; 75(6): 1119–1125.e1. 10.1016/j.jaad.2016.07.017 PubMedWeb of Science®Google Scholar 7Nutten S. Atopic dermatitis: global epidemiology and risk factors. Ann Nutr Metab. 2015; 66(Suppl. 1): 8–16. 10.1159/000370220 CASPubMedWeb of Science®Google Scholar 8Fadadu RP, Abuabara K, Balmes JR, Hanifin JM, Wei ML. Air pollution and atopic dermatitis, from molecular mechanisms to population-level evidence: a review. Int J Environ Res Public Health. 2023; 20(3): 2526. 10.3390/ijerph20032526 CASPubMedGoogle Scholar 9Ahn K. The role of air pollutants in atopic dermatitis. J Allergy Clin Immunol. 2014; 134(5): 993–999. 10.1016/j.jaci.2014.09.023 CASPubMedWeb of Science®Google Scholar 10Kimata H. Exposure to road traffic enhances allergic skin wheal responses and increases plasma neuropeptides and neurotrophins in patients with atopic eczema/dermatitis syndrome. Int J Hyg Environ Health. 2004; 207(1): 45–49. 10.1078/1438-4639-00261 PubMedGoogle Scholar Early ViewOnline Version of Record before inclusion in an issue ReferencesRelatedInformation

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