Tuning multiple enzyme-like activities by metal doping for identification and quantitation of antioxidants in cosmetics

化妆品 化学 鉴定(生物学) 色谱法 金属 组合化学 生物化学 有机化学 生物 植物
作者
Sheng-Tao Wu,Hui-Qi Su,Kai-Lin Shen,Ying Li,Yi Ge,Xiu-Fang Cheng,Changming Nie,Conghui Wang,Ying‐Wu Lin
出处
期刊:Chemical Engineering Journal [Elsevier BV]
卷期号:491: 152120-152120 被引量:2
标识
DOI:10.1016/j.cej.2024.152120
摘要

Inspired by the hydrolysis behaviors of skin cells, we exquisitely designed and synthesized a class of hydrolase mimics to develop an analytical method that can both identify and quantity antioxidant components in skin-whitening cosmetics, including ascorbic acid (AA) and its glycoside and phosphate derivatives. A series of ultra-thin Cu1-xMnxO2 or Fe1-yMnyO2 with rich acid-base pairs were prepared via chemical deposition and in-situ CuI/FeII self-assembly. H218O and D216O isotopic labeling studies and density function theory (DFT) calculations were adopted to analyze the cleaving sites of ascorbyl phosphate (AAL)/ascorbyl glucoside (AAP) and confirm that H2O was involved in the new bonds. In-situ DRIFT NH3-IR and −TPD further confirmed that the Fe- or Cu-substitution could increase the quantity and strength of Brønsted and Lewis acid sites. A cascade catalytic fluorescence sensor was designed for selective recognition or quantification of AA and its derivatives, which presents ultra-high-precision (≤2.5 %), stability, and selectivity in testing the target ingredients of five cosmetics from the market. Our nanozymes exhibit higher catalytic efficiency of 17.1 s−1 for AA, 8.42 s−1 for AAL, and 3.32 s−1 for AAP, which are 5.6 ∼ 32.8-fold higher than those of their mimic proteases. This work provides a controllable methodology to design hydrolytic nanozymes, which sheds light on biomimetic engineering and paves the way for breakthroughs in cosmetics industrial applications in the future.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
wwewew完成签到,获得积分10
1秒前
saying发布了新的文献求助10
1秒前
123123完成签到,获得积分10
1秒前
隐形曼青应助阿卡宁采纳,获得10
2秒前
负责紊完成签到,获得积分10
2秒前
善良的火发布了新的文献求助10
4秒前
haha完成签到,获得积分10
4秒前
6秒前
sugar完成签到,获得积分10
7秒前
活在当下完成签到,获得积分10
7秒前
9秒前
ssy发布了新的文献求助10
9秒前
小嘉贞完成签到,获得积分10
11秒前
鸡蛋黄完成签到,获得积分10
12秒前
温纲完成签到,获得积分10
13秒前
lalafish完成签到,获得积分10
13秒前
研友_nV2Kyn完成签到,获得积分10
14秒前
王冉冉发布了新的文献求助10
14秒前
铁甲小宝完成签到,获得积分10
15秒前
ssy完成签到,获得积分10
17秒前
低头应助gtt采纳,获得10
19秒前
芝士momoRIN完成签到,获得积分10
19秒前
wxx完成签到,获得积分10
20秒前
yar应助时尚的闭月采纳,获得10
21秒前
酷波er应助时尚的闭月采纳,获得10
21秒前
量子星尘发布了新的文献求助10
23秒前
zy完成签到 ,获得积分10
24秒前
花Cheung完成签到,获得积分10
24秒前
24秒前
24秒前
aliu完成签到,获得积分10
26秒前
小麻豆完成签到,获得积分10
26秒前
瓜农完成签到,获得积分10
27秒前
东篱发布了新的文献求助10
28秒前
科研通AI2S应助端己采纳,获得10
28秒前
香蕉觅云应助王冉冉采纳,获得10
30秒前
31秒前
Mmoler完成签到 ,获得积分10
32秒前
大模型应助海上钢琴家采纳,获得10
33秒前
lzhgoashore应助sl采纳,获得10
33秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
Research on Disturbance Rejection Control Algorithm for Aerial Operation Robots 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038524
求助须知:如何正确求助?哪些是违规求助? 3576221
关于积分的说明 11374737
捐赠科研通 3305912
什么是DOI,文献DOI怎么找? 1819354
邀请新用户注册赠送积分活动 892688
科研通“疑难数据库(出版商)”最低求助积分说明 815048