超氧化物歧化酶
丙二醛
氧化应激
脂质过氧化
过氧化氢酶
谷胱甘肽过氧化物酶
抗氧化剂
活性氧
化学
生物化学
过氧化物酶
谷胱甘肽
酶
作者
Maria do Carmo de Carvalho e Martins,Amanda Suellenn da Silva Santos Oliveira,Liriane Andressa Alves da Silva,Maísa Guimarães Silva Primo,Vanessa Brito de Carvalho Lira
出处
期刊:Biomarkers in disease
日期:2022-01-01
卷期号:: 833-856
被引量:10
标识
DOI:10.1007/978-3-031-07389-2_49
摘要
The imbalance between the oxidant and antioxidant systems leads to a biological condition defined as oxidative stress that contributes to the formation of reactive oxygen species, which are unstable molecules resulting from various processes in the body that can be highly harmful and cause a series of diseases. In this sense, the action of antioxidants becomes necessary, as they are responsible for inhibiting and reducing damage caused by free radicals in cells. However, it is possible to prevent the damage caused by exposure to pro-oxidant substances through the measurement of biological biomarkers, which are important in the evaluation of the redox state. In this chapter, we will discuss markers used to assess the capacity of free radical scavenging, such as catalase, glutathione peroxidase, and superoxide dismutase enzymes, in addition to malondialdehyde, a biomarker used to assess lipid peroxidation. Oxidative stress biomarkers have been studied in several pathologies and can help in the diagnosis and monitoring of the progression of these diseases.
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