Obstructive sleep apnea and cardiovascular events in acute coronary syndrome: a meta-analysis

医学 阻塞性睡眠呼吸暂停 荟萃分析 内科学 急性冠脉综合征 危险系数 狼牙棒 观察研究 置信区间 子群分析 出版偏见 科克伦图书馆 心绞痛 心脏病学 心肌梗塞 传统PCI
作者
Jiangtao Tong,Qian Yu,Yuan Li,Jianbo Du,Jian Qiu
出处
期刊:Coronary Artery Disease [Lippincott Williams & Wilkins]
卷期号:34 (3): 177-184 被引量:3
标识
DOI:10.1097/mca.0000000000001207
摘要

Obstructive sleep apnea (OSA) in patients with the acute coronary syndrome (ACS) were at high risk for cardiovascular events, but the results are currently inconclusive. We aimed to conduct a systematic review to determine the incidence of cardiovascular events among ACS patients with OSA by a meta-analysis of observational studies.PubMed, Embase, and Cochrane Library were searched for studies related to the association between OSA and the risk of cardiovascular events in patients with ACS. Risk of bias in observational studies was assessed according to the Risk Of Bias In the Non-randomized Studies-Of Interventions tool.We performed a meta-analysis using a random-effects model to calculate estimates of pooled hazard ratios (HR) with 95% confidence intervals (CI), and heterogeneity was assessed using the statistics.A total of 12 studies evaluating ACS patients with OSA were included in the meta-analysis. OSA was related to the increased risk of MACE (HR = 2.2; 95% CI, 1.274-3.805, I2 = 76.1%). The effect of OSA on MACCE (HR = 1.921; 95% CI, 1.45-2.546; I2 = 19.1%) and readmission for unstable angina (HR = 3.137, 95% CI, 1.06-9.283; I2 = 52.4%) were statistically significant in the pooled analysis. All of the outcomes in the included studies had a serious risk of bias and the Grading of Recommendation, Assessment, Development, and Evaluation evidence level of all the evaluation results were very low.OSA was associated with a significant increase in the risk of cardiovascular events for patients with ACS. Additional randomized controlled trial studies are required to confirm the results and to prove the treatment of OSA can change the prognosis.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
C陈完成签到,获得积分10
1秒前
2秒前
suger发布了新的文献求助10
3秒前
4秒前
干雅柏完成签到,获得积分10
5秒前
八九完成签到,获得积分10
6秒前
7秒前
干雅柏发布了新的文献求助10
8秒前
Stardust发布了新的文献求助10
8秒前
黑白和完成签到 ,获得积分10
9秒前
yang完成签到,获得积分10
10秒前
金蛋蛋发布了新的文献求助10
11秒前
量子星尘发布了新的文献求助10
13秒前
17秒前
22秒前
淡定的电源完成签到,获得积分10
25秒前
25秒前
lm发布了新的文献求助10
28秒前
30秒前
善学以致用应助孤独问旋采纳,获得10
30秒前
孙燕应助霸气安筠采纳,获得30
31秒前
李健应助科研通管家采纳,获得10
31秒前
汉堡包应助科研通管家采纳,获得10
31秒前
SYLH应助科研通管家采纳,获得20
31秒前
SYLH应助科研通管家采纳,获得10
31秒前
上官若男应助科研通管家采纳,获得10
31秒前
烟花应助科研通管家采纳,获得10
31秒前
丘比特应助科研通管家采纳,获得10
31秒前
SYLH应助科研通管家采纳,获得10
32秒前
CAOHOU应助科研通管家采纳,获得10
32秒前
SYLH应助科研通管家采纳,获得10
32秒前
CAOHOU应助科研通管家采纳,获得10
32秒前
SYLH应助科研通管家采纳,获得10
32秒前
科研通AI2S应助科研通管家采纳,获得10
32秒前
JamesPei应助科研通管家采纳,获得10
32秒前
ding应助科研通管家采纳,获得10
32秒前
32秒前
SYLH应助科研通管家采纳,获得10
32秒前
CAOHOU应助科研通管家采纳,获得10
32秒前
SYLH应助科研通管家采纳,获得20
32秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989378
求助须知:如何正确求助?哪些是违规求助? 3531442
关于积分的说明 11254002
捐赠科研通 3270126
什么是DOI,文献DOI怎么找? 1804887
邀请新用户注册赠送积分活动 882087
科研通“疑难数据库(出版商)”最低求助积分说明 809173