A Window into the Developing Brain: Toward a Deeper Understanding of Pediatric Anesthesia

Editorial| May 2024 A Window into the Developing Brain: Toward a Deeper Understanding of Pediatric Anesthesia This article has an Audio Podcast Jerry Y. Chao, M.D., M.Sc.; Jerry Y. Chao, M.D., M.Sc. 1Department of Anesthesiology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York. https://orcid.org/0000-0001-8666-7583 Search for other works by this author on: This Site PubMed Google Scholar Allan F. Simpao, M.D., M.B.I.; Allan F. Simpao, M.D., M.B.I. 2Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Department of Anesthesiology and Critical Care, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania. https://orcid.org/0000-0001-8871-2579 Search for other works by this author on: This Site PubMed Google Scholar Ian Yuan, M.D., M.Eng. Ian Yuan, M.D., M.Eng. 3Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Department of Anesthesiology and Critical Care, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania. https://orcid.org/0000-0002-4821-0360 Search for other works by this author on: This Site PubMed Google Scholar Author and Article Information This editorial accompanies the article on p. 890. This article has a related Infographic on p. A16. Accepted for publication January 22, 2024. Address correspondence to Dr. Chao: Anesthesiology May 2024, Vol. 140, 863–864. https://doi.org/10.1097/ALN.0000000000004937 Connected Content Article: Topographical Features of Pediatric Electroencephalography during High Initial Concentration Sevoflurane for Inhalational Induction of Anesthesia Infographic: Itsy Bitsy Inductions: The Effect of High-dose Sevoflurane Following Loss of Consciousness in Children Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Search Site Citation Jerry Y. Chao, Allan F. Simpao, Ian Yuan; A Window into the Developing Brain: Toward a Deeper Understanding of Pediatric Anesthesia. Anesthesiology 2024; 140:863–864 doi: https://doi.org/10.1097/ALN.0000000000004937 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll PublicationsAnesthesiology Search Advanced Search Topics: brain, pediatric anesthesia, electroencephalography, child General anesthesia induces dramatic neurophysiological changes that can be observed on the electroencephalogram (EEG). In this month's issue of Anesthesiology, Martin et al. used high-density EEG in 23 children with ages ranging from 5 to 10 yr to better understand the effects of sevoflurane induction on the developing brain.1 Unlike pediatric EEG studies that have focused on the maintenance or emergence phases of anesthesia, this study examined the period of induction shortly after loss of consciousness associated with dynamic clinical and EEG changes. The investigators obtained EEG data during the eyes-closed, awake baseline state and compared these to the EEG during the minute after loss of consciousness from a high inspired concentration of sevoflurane. They report the main finding of significantly increased signal intensity (i.e., power) in the delta (1 to 4 Hz) frequency band after loss of consciousness without topographical differences between age groups.... You do not currently have access to this content.