[Chinese expert consensus on the application of circulating tumor cell detection in the diagnosis and treatment of gastrointestinal neoplasms (2023 edition)].

Circulating tumor cell (CTC), as a novel tumor marker, has the characteristics of non-invasive, dynamic monitoring and high accuracy, and provides precise molecular characteristics of tumors and helps understand the changes in tumor development. Therefore, CTC has important clinical value in the dynamic monitoring of tumor progression. In order to standardize and guide the application of CTC detection in the diagnosis and treatment of gastrointestinal neoplasms, Gastric Cancer Group of Oncology Branch of Chinese Medical Association, Colorectal Cancer Professional Committee of Chinese Medical Doctor Association, Colorectal Cancer Professional Committee of Chinese Anti-Cancer Association, Gastric Cancer Professional Committee of Chinese Anti-Cancer Association, Digestive Tract Polyp and Precancerous Lesion Professional Committee of Chinese Anti-Cancer Association, jointly convened some domestic experts to discuss and formulate the Chinese expert consensus on the application of circulating tumor cell detection in the diagnosis and treatment of gastrointestinal neoplasms (2023 edition). The consensus provides opinions on the detection technology and clinical application of CTC detection in the diagnosis and treatment of gastrointestinal neoplasms, including the prediction of tumor prognosis, the monitoring of tumor recurrence and metastasis, the evaluation of treatment response, and the additional diagnostic value, providing guidance for clinical application.循环肿瘤细胞（CTC）作为新型的肿瘤标志物，具有无创、动态监测和高准确度等特点，可以提供精确的肿瘤分子特征，帮助了解肿瘤发展过程中的变化。因此，CTC在肿瘤进展的动态监测中具有重要临床价值。为了规范和指导CTC检测在胃肠道肿瘤诊疗中的应用，中华医学会肿瘤学分会胃癌学组、中国医师协会结直肠肿瘤专业委员会、中国抗癌协会大肠癌专业委员会、中国抗癌协会胃癌专业委员会、中国抗癌协会消化道息肉及癌前病变专业委员会共同发起并召集国内部分专家，讨论制定了《循环肿瘤细胞检测在胃肠道肿瘤诊疗中的应用专家共识（2023版）》。该共识围绕CTC检测在胃肠道肿瘤诊疗中的检测技术和临床应用，包括预后判断、复发转移的监测、疗效监测和辅助诊断等方面，提供了共识意见，以期为临床应用提供指导。.