New stable high-drug-loading amorphous solid dispersions from electrospinning

Electrospinning is a technique that can be used to fabricate amorphous solid dispersions and thus overcome the major challenge of poor drug solubility. However, the majority of studies in the literature work at relatively low drug loadings (<30% w/w). Recent work by Becelaere et al. to overcome this challenge and increase loading to >50% is discussed in this preview. Electrospinning is a technique that can be used to fabricate amorphous solid dispersions and thus overcome the major challenge of poor drug solubility. However, the majority of studies in the literature work at relatively low drug loadings (<30% w/w). Recent work by Becelaere et al. to overcome this challenge and increase loading to >50% is discussed in this preview.