Developments of solid phase micro-extraction techniques

Sample preparation is the bottleneck of analytical chemistry. 1987 introduction of the solid phase micro-extraction( SPME) has brought significant progress in the sample preparation area. Some kinds of new coatings appeared in recent years. These new coatings extend the application of SPME in fields of onsite and in vivo analysis. This paper reviewed developments of solid phase micro-extraction modes,it including fiber solid phase micro extraction,in-tube solid phase micro extraction,stir-bar surptive extraction,and their future development is predicted.