<title>Lifetime-resolved fluorescence-detected circular dichroism: a new technique for probing macromolecular structures</title>

Theory and instrumentation of lifetime-resolved fluorescence-detected circular dichroism spectroscopy (LRFDCD) are described. Advantages of LRFDCD over the individual techniques of fluorescence lifetime determinations and circular dichroism spectroscopy are discussed. LRFDCD is implemented on a frequency-domain fluorescence lifetime instrument that is modified for fluorescence-detected circular dichroism measurements.