神经调节
最小意识状态
医学
神经科学
意识
脑深部刺激
神经外科
神经学
骶神经电刺激
持续植物状态
刺激
心理学
精神科
外科
内科学
疾病
帕金森病
作者
Pier Paolo Mattogno,Giuseppe Barbagallo,Domenico Gerardo Iacopino,Gaetano Pappalardo,Giuseppe La Rocca,Francesco Signorelli,Jun Zhong,Massimiliano Visocchi
出处
期刊:Acta neurochirurgica
日期:2017-01-01
卷期号:: 19-25
被引量:20
标识
DOI:10.1007/978-3-319-39546-3_4
摘要
Chronic diseases of consciousness (CDC) can still be considered a challenging frontier for modern medicine, probably because of their not completely understood physiopathological mechanisms. Following encouraging evidence on cerebral hemodynamics, some authors have hypothesized a role for neuromodulation in the treatment of CDC patients. In the past 40 years, spinal cord stimulation (SCS) and deep brain stimulation (DBS) have been used experimentally for the treatment of patients in a severe altered state of consciousness, with some interesting but not conclusive results. The present review summarizes the data currently available in the literature on this particular and debated topic. On these grounds, further clinical studies are needed to better understand the altered dynamics of neuronal network circuits in CDC patients as a step towards novel therapeutic strategies.
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