Transplantation of ACE2- Mesenchymal Stem Cells Improves the Outcome of Patients with COVID-19 Pneumonia

A coronavirus (HCoV-19) has caused the novel coronavirus disease (COVID-19) outbreak in Wuhan, China.Preventing and reversing the cytokine storm may be the key to save the patients with severe COVID-19 pneumonia.Mesenchymal stem cells (MSCs) have been shown to possess a comprehensive powerful immunomodulatory function.This study aims to investigate whether MSC transplantation improves the outcome of 7 enrolled patients with COVID-19 pneumonia in Beijing YouAn Hospital, China, from Jan 23, 2020 to Feb