Antioxidant and anti-inflammatory effect of oleuropein in hepatic steatosis

Introduction: Nonalcoholic fatty liver disease (NAFLD), or liver steatosis, is a common hepatic disease in which oxidative stress plays a main role in causing liver damage. Fat metabolism is dependent on mitochondrial activity that generates ATP but also reactive oxygen species (ROS). Oleuropein (Ole) is a phenolic compound with significant antioxidant and anti-inflammatory properties.