HA targeted-biodegradable nanocomposites responsive to endogenous and exogenous stimulation for multimodal imaging and chemo-/photothermal therapy

A tumor-targeted, on-demand chemo-/photothermal therapeutic nanoplatform (HIDSi_GdNPs@PDA-HA) based on degradable HMONs was used for bimodal imaging and endogenous and exogenous multi-factor stepwise response for drug release and treatment.