最小临床重要差异
医学
止痛药
急性疼痛
物理疗法
术后疼痛
重症监护医学
麻醉
随机对照试验
外科
作者
Felipe Muñoz-Leyva,Kariem El‐Boghdadly,V Chan
出处
期刊:Regional Anesthesia and Pain Medicine
[BMJ]
日期:2020-09-07
卷期号:45 (12): 1000-1005
被引量:45
标识
DOI:10.1136/rapm-2020-101670
摘要
In the field of acute pain medicine research, we believe there is an unmet need to incorporate patient related outcome measures that move beyond reporting pain scores and opioid consumption. The term “minimal clinically important difference” (MCID) defines the clinical benefit of an intervention as perceived by the patient, as opposed to a mathematically determined statistically significant difference that may not necessarily be clinically significant. The present article reviews the concept of MCID in acute postoperative pain research, addresses potential pitfalls in MCID determination and questions the clinical validity of extrapolating MCID determined from chronic pain and non-surgical pain studies to the acute postoperative pain setting. We further suggest the concepts of minimal clinically important improvement, substantial clinical benefit and patient acceptable symptom state should also represent aspirational outcomes for future research in acute postoperative pain management.
科研通智能强力驱动
Strongly Powered by AbleSci AI