The effect of “Curcuma Longa” topical gel on radiation-induced oral mucositis in patients with head and neck cancer

姜黄 医学 粘膜炎 放射治疗 头颈部癌 头颈部 安慰剂 癌症 皮肤病科 内科学 传统医学 外科 病理 替代医学
作者
A. Mansourian,Massoud Amanlou,Sh . Shirazian,Z Moosavian Jahromi,Aslan Amirian
标识
DOI:10.7508/ijrr.2015.03.011
摘要

Background: Different treatment and protecve approaches for radiaon- induced oral mucosis have been pracced and have variees of success. Of which, radioprotecve agents, synthec or natural, have been of great interest for researchers. This study aims to evaluate the ef fect of curcuma longa topical gel as a herbal producon on mucosis induced by radiaon therapy of head and neck cancers. Materials and Methods: Thirty seven paents with head and neck cancer admi ed for radiaon therapy were selected. The paents were given curcuma longa or placebo topical gel for 8 weeks since the iniaon of the radiotherapy, and were evaluated weekly for the presence and the extent of oral mucosis. Results: No grade-3 mucosis was observed in paents who used curcuma longa topical gel, and the grade of the mucosis was significantly different between the two groups with be er effects found in case group compared to controls. No significant difference between the case and control groups was observed when comparing theme of appearing the first signs of mucosis. Oral lesions in case group were significantly smaller than that of control group. Conclusion: This study showed that the topical gel, containing curcuma longa's derivate, can effecvely reduce the oral symptoms of mucosis in paents undergoing head and neck cancer radiotherapy. This herbal drug improves the grade of mucosis and reduces the size of oral lesions resulng from radiotherapy to the head and neck region.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
tovfix完成签到,获得积分10
1秒前
Chem发布了新的文献求助10
3秒前
科研通AI2S应助研友_8oYMyn采纳,获得10
3秒前
ywayw发布了新的文献求助10
5秒前
6秒前
搜集达人应助青儿采纳,获得30
7秒前
taniou完成签到,获得积分10
7秒前
欢呼败完成签到 ,获得积分10
8秒前
不木羊发布了新的文献求助10
8秒前
无花果应助跳跃的冬灵采纳,获得10
9秒前
10秒前
beituo发布了新的文献求助10
11秒前
12秒前
冷酷莫茗发布了新的文献求助10
13秒前
科研通AI2S应助害羞电灯胆采纳,获得10
14秒前
14秒前
妩媚的夏旋完成签到,获得积分10
15秒前
无花果应助蜡笔小新采纳,获得10
15秒前
15秒前
李健的小迷弟应助beituo采纳,获得10
15秒前
六天发布了新的文献求助10
16秒前
Akim应助hqr采纳,获得10
16秒前
16秒前
19秒前
nn发布了新的文献求助10
19秒前
科研通AI2S应助人民群众采纳,获得10
20秒前
Owen应助bemyselfelsa采纳,获得10
20秒前
桐桐应助妩媚的夏旋采纳,获得10
21秒前
21秒前
天宝发布了新的文献求助30
21秒前
哈桑士发布了新的文献求助10
22秒前
23秒前
zhenggggg完成签到,获得积分10
24秒前
24秒前
25秒前
25秒前
冷静的画笔完成签到 ,获得积分10
25秒前
一区哥完成签到,获得积分10
25秒前
Ava应助活力的妙菡采纳,获得10
25秒前
林宥嘉发布了新的文献求助10
26秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Picture Books with Same-sex Parented Families: Unintentional Censorship 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
A Preliminary Study on Correlation Between Independent Components of Facial Thermal Images and Subjective Assessment of Chronic Stress 500
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3972225
求助须知:如何正确求助?哪些是违规求助? 3516715
关于积分的说明 11184237
捐赠科研通 3252126
什么是DOI,文献DOI怎么找? 1796253
邀请新用户注册赠送积分活动 876339
科研通“疑难数据库(出版商)”最低求助积分说明 805483