In vitro Approaches of Primula vulgaris Leaves and Roots Extraction against Human Pathogenic Bacterial Strains

2 Abstract: Primula is a medicinal plant bearing flowers which belongs to family Primulaceae. These are low growing herbs. Methanol and cold water extraction methods were used for leaves and roots extractions of Primulavulgaris. Antimicrobial activity ofleaves and roots extracts was evaluated by well diffusion method. Results revealed that P. vulgaris leaves extractexhibit excellent inhibitory effects against Escherichia coli that showed zone of inhibition 18 mm with methanol extract and 14 mm with cold water extract and Pseudomonas aeruginosa showed zone of inhibition 14 mm with methanol extract and 13 mm with cold water extract. Roots extract of P. vulgaris also exhibited inhibitory effects against E. coli showed zone of inhibition 13 mm with methanol extract and 16 mm with cold water extract and P. aeruginosa showed zone of inhibition 13 mm with methanol extract and 14mm with cold water extract while Staphylococcus aureus did not show any inhibitory zone with leaves or roots extracts. This research summarized that leaves and roots extracts of P. vulgaris contains a brought range of antimicrobial activity against the microorganism. Advance studies should carry out to find out the precise method of action by which extracts exert their antimicrobial effect to recognize which can be used in drug development.