PHARMACOLOGICAL ACTIONS OF CORLUMINE

A new alkaloid, corlumine, was studied and contrasted with one of its stereoisomers, adlumine, and compared with the chemically related alkaloids hydrastine and bicuculline. General similarities of action between all members of the group are present as the chemical similarities would indicate. But differences of action are evident not only between chemically different alkaloids, but also between the stereoisomers, adlumine and corlumine, and these latter differences are at least as marked as those due to slight chemical variations in the alkaloids.