医学
心脏病学
内科学
向心性肥大
肌肉肥大
左心室肥大
心肌梗塞
氯沙坦
血压
心室重构
弗雷明翰风险评分
临床终点
血管紧张素II
随机对照试验
作者
Eva Gerdts,Dana Cramariuc,Giovanni de Simone,Kristian Wachtell,Björn Dahlöf,Richard B. Devereux
出处
期刊:European journal of echocardiography
[Oxford University Press]
日期:2008-05-10
卷期号:9 (6): 809-815
被引量:145
标识
DOI:10.1093/ejechocard/jen155
摘要
AimsLess is known about the relation between in-treatment left ventricular (LV) geometry and risk of cardiovascular events. We assessed LV geometric patterns on baseline and annual echocardiograms as time-varying predictors of the primary composite endpoint (cardiovascular death, stroke, and myocardial infarction) in 937 hypertensive patients with LV hypertrophy during 4.8 years losartan- or atenolol-based treatment in the Losartan Intervention for Endpoint reduction in hypertension (LIFE) echocardiography substudy.
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