Nomogram to Predict 90-Day All-Cause Mortality in Acute Ischemic Stroke Patients after Endovascular Thrombectomy

列线图 医学 逻辑回归 闭塞 冲程(发动机) 内科学 多元统计 多元分析 心脏病学 外科 机械工程 工程类 统计 数学
作者
Shiya Zhang,Shuai Yu,Xiaocui Wang,Zhiliang Guo,Jie Hou,Huaishun Wang,Zhichao Huang,Guodong Xiao,Shoujiang You
出处
期刊:Current Neurovascular Research [Bentham Science Publishers]
卷期号:21 (3): 243-252 被引量:2
标识
DOI:10.2174/0115672026311086240415050048
摘要

Objective: Although Endovascular Thrombectomy (EVT) significantly improves the prognosis of Acute Ischemic Stroke (AIS) patients with large vessel occlusion, the mortality rate remains higher. This study aimed to construct and validate a nomogram for predicting 90-day all-cause mortality in AIS patients with large vessel occlusion and who have undergone EVT. Methods: AIS patients with large vessel occlusion in the anterior circulation who underwent EVT from May 2017 to December 2022 were included. 430 patients were randomly split into a training group (N=302) and a test group (N=128) for the construction and validation of our nomogram. In the training group, multivariate logistic regression analysis was performed to determine the predictors of 90-day all-cause mortality. The C-index, calibration plots, and decision curve analysis were applied to evaluate the nomogram performance. Results: Multivariate logistic regression analysis revealed neurological deterioration during hospitalization, age, baseline National Institutes of Health Stroke Scale (NIHSS) score, occlusive vessel location, malignant brain edema, and Neutrophil-to-lymphocyte Ratio (NLR) as the independent predictors of 90-day all-cause mortality (all p ≤ 0.039). The C-index of the training and test groups was 0.891 (95%CI 0.848-0.934) and 0.916 (95% CI: 0.865-0.937), respectively, showing the nomogram to be well distinguished. The Hosmer-Lemeshow goodness-of-fit test revealed the p-values for both the internal and external verification datasets to be greater than 0.5. Conclusion: Our nomogram has incorporated relevant clinical and imaging features, including neurological deterioration, age, baseline NIHSS score, occlusive vessel location, malignant brain edema, and NLR ratio, to provide an accurate and reliable prediction of 90-day all-cause mortality in AIS patients undergoing EVT.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
ding应助JX采纳,获得10
1秒前
玉尘完成签到,获得积分20
1秒前
2秒前
orixero应助Plutus采纳,获得10
2秒前
2秒前
Junlian发布了新的文献求助10
2秒前
3秒前
Shen发布了新的文献求助10
3秒前
3秒前
3秒前
3秒前
打打应助hhh采纳,获得10
3秒前
JQB完成签到,获得积分10
3秒前
共享精神应助单薄的忆枫采纳,获得10
4秒前
Akim应助顾年采纳,获得10
4秒前
4秒前
6秒前
6秒前
heiztcasino发布了新的文献求助10
6秒前
量子星尘发布了新的文献求助10
7秒前
7秒前
8秒前
小蚊子发布了新的文献求助10
8秒前
qiaoj2006完成签到,获得积分10
8秒前
许欣瑞完成签到,获得积分10
8秒前
CipherSage应助ldy采纳,获得10
8秒前
tectextey发布了新的文献求助10
9秒前
万能图书馆应助KYTQQ采纳,获得20
10秒前
保住头发为科研完成签到,获得积分10
11秒前
田様应助北纬打工人采纳,获得10
11秒前
科目三应助无心的青槐采纳,获得20
11秒前
heiztcasino完成签到,获得积分10
11秒前
大个应助科研通管家采纳,获得10
12秒前
彭于晏应助晚霞常有遗憾采纳,获得10
12秒前
李爱国应助科研通管家采纳,获得10
12秒前
科研通AI6应助科研通管家采纳,获得10
12秒前
攀攀发布了新的文献求助10
12秒前
领导范儿应助科研通管家采纳,获得10
12秒前
共享精神应助科研通管家采纳,获得10
12秒前
高分求助中
(应助此贴封号)【重要!!请各用户(尤其是新用户)详细阅读】【科研通的精品贴汇总】 10000
计划经济时代的工厂管理与工人状况(1949-1966)——以郑州市国营工厂为例 500
INQUIRY-BASED PEDAGOGY TO SUPPORT STEM LEARNING AND 21ST CENTURY SKILLS: PREPARING NEW TEACHERS TO IMPLEMENT PROJECT AND PROBLEM-BASED LEARNING 500
The Pedagogical Leadership in the Early Years (PLEY) Quality Rating Scale 410
Stackable Smart Footwear Rack Using Infrared Sensor 300
Modern Britain, 1750 to the Present (第2版) 300
Writing to the Rhythm of Labor Cultural Politics of the Chinese Revolution, 1942–1976 300
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 纳米技术 计算机科学 内科学 化学工程 复合材料 物理化学 基因 催化作用 遗传学 冶金 电极 光电子学
热门帖子
关注 科研通微信公众号,转发送积分 4603484
求助须知:如何正确求助?哪些是违规求助? 4012177
关于积分的说明 12422449
捐赠科研通 3692673
什么是DOI,文献DOI怎么找? 2035749
邀请新用户注册赠送积分活动 1068916
科研通“疑难数据库(出版商)”最低求助积分说明 953403