Dose‐response analysis between alcohol consumption and psoriasis: A systematic review and meta‐analysis

银屑病 优势比 医学 置信区间 荟萃分析 饮酒量 队列研究 内科学 环境卫生 人口学 皮肤病科 生物 生物化学 社会学
作者
Jeeyu Choi,Ikjoon Han,Joohong Min,Jisang Yun,Byung Soo Kim,Kihyuk Shin,Kihun Kim,Yun Hak Kim
出处
期刊:Journal der Deutschen Dermatologischen Gesellschaft [Wiley]
卷期号:22 (5): 641-652 被引量:2
标识
DOI:10.1111/ddg.15380
摘要

Summary The association between psoriasis and alcohol consumption has been inconsistent across various studies. However, to the best of our knowledge, no dose‐response meta‐analysis has been performed to date. This study aims to investigate the association between alcohol consumption and psoriasis. The search was performed on July 27, 2021, using Embase and MEDLINE. The restricted cubic spline analysis was used to perform a dose‐response analysis. We identified 3,904 studies, of which 48 studies with 1,702,847 individuals across 24 countries were included. Alcohol consumption was positively associated with psoriasis (odds ratio [OR], 1.47; 95% confidence interval [CI], 1.27‐1.70). In addition, a significantly increased OR for psoriasis was observed in males (OR, 1.84; 95% CI, 1.13–3.01) but not in females (OR, 1.22; 95% CI, 0.97–1.54). Based on eight studies, including three cohort and five case‐control studies, the analysis revealed that with each additional gram of daily alcohol intake, the OR for psoriasis increased by 4%. We found a positive association between alcohol consumption and psoriasis. The association is more prominent in the group drinking more than 45 g of alcohol per day (3.2 alcoholic drink equivalent).
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