pH-driven fabrication of a caseinate–pectin polyelectrolyte complex as a promising carrier for lutein and zeaxanthin delivery: Microencapsulation, stability, and sustained release properties

叶黄素 果胶 玉米黄质 聚电解质 化学 制作 化学工程 控制释放 纳米技术 材料科学 食品科学 有机化学 类胡萝卜素 聚合物 医学 替代医学 病理 工程类
作者
Gang Zhang,Yuqian Yan,Linlin He,Xin Qi,Yanna Zhao,Xiao Wang,Min Liu,Zhuang Ding,Zhengping Wang,Paul Van der Meeren
出处
期刊:International Journal of Biological Macromolecules [Elsevier]
卷期号:: 136101-136101
标识
DOI:10.1016/j.ijbiomac.2024.136101
摘要

In this study, caseinate-pectin polyelectrolyte complexes and co-solutions were successfully fabricated at pH 3.0 and 7.0, respectively, to encapsulate bioactive molecules. During the fabrication process, the effect of the sequence in which each component was added on lutein/zeaxanthin (Lut/Zx) complexation with sodium caseinate (NaCas) was investigated. The protective effect of the polyelectrolyte complex and co-solution for Lut/Zx in liquid formulations was compared with that of a binary system containing only caseinate and Lut/Zx. Compared with the binary system, the polyelectrolyte complex at pH 3.0 further enhanced the chemical stability of Lut/Zx during storage, whereas the co-solution at pH 7.0 did not exhibit this ability. Unexpectedly, NaCas-Lut/Zx - pectin (NC-L/Z-P) with a theoretically sandwich structure did not exhibit better protection than NaCas-pectin-Lut/Zx (NC-P-L/Z). Fluorescence quenching spectra revealed that the addition of NaCas to Lut/Zx and ultimately to pectin resulted in the formation of a sandwich structure, which was soon followed by structural rebalancing. Finally, freshly prepared NC-L/Z-P complexes were lyophilized to stabilize their sandwich structure, resulting in improved encapsulation and sustained-release properties compared with those of the dried NC-P-L/Z. These results suggest that protein-polysaccharide complexes, combined with timely dehydration, enhance the combination of Lut/Zx with caseinate, leading to heightened protective effects.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
1秒前
2秒前
2秒前
5秒前
天天快乐应助白耳猫采纳,获得10
7秒前
多多发布了新的文献求助10
7秒前
8秒前
8秒前
吾皇完成签到 ,获得积分10
9秒前
我是老大应助自信的不悔采纳,获得10
12秒前
jimmy发布了新的文献求助10
14秒前
14秒前
星移发布了新的文献求助10
15秒前
陈最发布了新的文献求助10
17秒前
坚强枫完成签到,获得积分10
17秒前
19秒前
不配.应助abai采纳,获得10
19秒前
空山发布了新的文献求助30
19秒前
浅笑初妍给美嘉美的求助进行了留言
20秒前
白耳猫完成签到,获得积分10
20秒前
科研星发布了新的文献求助10
21秒前
21秒前
夏天再见发布了新的文献求助10
21秒前
攒星星完成签到,获得积分10
22秒前
23秒前
23秒前
白耳猫发布了新的文献求助10
24秒前
24秒前
24秒前
24秒前
25秒前
27秒前
科目三应助早上坏采纳,获得10
27秒前
领导范儿应助jimmy采纳,获得10
27秒前
是莉莉娅发布了新的文献求助30
28秒前
lisastream发布了新的文献求助10
28秒前
29秒前
29秒前
劲秉应助科研人员采纳,获得10
29秒前
高分求助中
Spray / Wall-interaction Modelling by Dimensionless Data Analysis 2000
Evolution 3rd edition 1500
ALA生合成不全マウスでの糖代謝異常の分子機構解析 520
Mathematics and Finite Element Discretizations of Incompressible Navier—Stokes Flows 500
A new species of Coccus (Homoptera: Coccoidea) from Malawi 500
2-Acetyl-1-pyrroline: an important aroma component of cooked rice 500
Handbook on People's China (1957) 400
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3189034
求助须知:如何正确求助?哪些是违规求助? 2838479
关于积分的说明 8019927
捐赠科研通 2501323
什么是DOI,文献DOI怎么找? 1335534
科研通“疑难数据库(出版商)”最低求助积分说明 637591
邀请新用户注册赠送积分活动 605656