Safety and Effectiveness of As-Needed Formoterol in Asthma Patients Taking Inhaled Corticosteroid (ICS)-Formoterol or ICS-Salmeterol Maintenance Therapy

What is already known about this topic?Global Initiative for Asthma (GINA) and National Asthma Education and Prevention Program (NAEPP) guidelines recommend inhaled corticosteroid (ICS)-formoterol as the preferred controller and reliever for asthma, either in combination with maintenance ICS-formoterol or (in GINA) alone.However, for patients taking a non-formoterol ICS-long-acting b 2 -agonist as maintenance therapy, the recommended reliever is a short-acting b 2 -agonist (SABA) or (in GINA 2023) combination ICS