医学
体外膜肺氧合
四分位间距
回顾性队列研究
单中心
急诊医学
外科
麻醉
作者
Nisha Agasthya,Curtis D. Froehlich,Michael Golecki,Marisa Meyer,Mark Ogino,Kendra Froehlich,Christopher D. Beaty,Sharon McCants,Timothy M. Maul,Daniel Dirnberger
出处
期刊:Pediatric Critical Care Medicine
[Ovid Technologies (Wolters Kluwer)]
日期:2022-12-26
卷期号:24 (4): e190-e195
被引量:5
标识
DOI:10.1097/pcc.0000000000003154
摘要
Extracorporeal membrane oxygenation (ECMO) systems have continued to evolve and improve with the development of smaller and portable systems. The Cardiohelp (Maquet Getinge Cardiopulmonary AG, Rastatt, Germany) portable life support device is a compact ECMO system used widely in adults and for ECMO transport. Reports of its use in neonatal and pediatric centers remain limited. In this single-center retrospective review, we describe our institutional experience with the Cardiohelp.Single-center retrospective review.Neonatal ICUs and PICUs in a tertiary-care children's hospital.Seventeen pediatric patients on ECMO.None.Median (interquartile range, IQR) of patient age was 0.5 years (0-7 yr). Eleven of 17 patients were on veno-arterial ECMO, five on veno-venous ECMO, and one on veno-venoarterial ECMO. All veno-venous and veno-venoarterial runs ( n = 6) were accomplished with bicaval, dual-lumen cannulae. Median duration on Cardiohelp was 113 hours (IQR 50-140 hr). Median anti-Xa level for patients was 0.43 IU/mL (IQR 0.35-0.47 IU/mL), with median heparin dose of 23.6 U/kg/hr (IQR 17.6-28.1 U/kg/hr). Median plasma-free hemoglobin was 41.4 mg/dL (IQR 30-60 mg/dL). Circuit change was required in three cases. Fourteen patients survived ECMO, with 13 patients surviving to discharge.We have used the Cardiohelp system to support 17 neonatal and pediatric ECMO patients, without complications. Further studies are warranted to compare complications, outcomes, and overall cost with other institutions and other existing ECMO systems.
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