Characteristics of vitiligo patients with versus without associated autoimmune thyroid disease

Abstract Background Clinical data are limited in patients with vitiligo with or without autoimmune thyroid disease. Objectives The objective of the study was to investigate the clinical features and basic data of patients with vitiligo, especially those with autoimmune thyroid disease. Methods The study was a single‐center retrospective study. A total of 1305 patients with vitiligo from June 2018 to May 2023 were included, and the clinical characteristics and basic information of the patients were recorded in detail. Results We identified an association between sex (odds ratio [OR]: 2.380; 95% confidence interval [CI]: 1.772–1.198), vitiligo duration (OR: 1.449; 95% CI: 1.076–1.952), skin involvement exceeding 5% of the body surface area (OR: 3.764; 95% CI: 2.134–6.640), negative emotions (OR: 3.076; 95% CI: 2.292–4.127), vitiligo type (OR: 1.974; 95% CI: 1.096–3.555), family history of AITD (OR: 4.979; 95% CI: 2.687–9.225), and family history of AD (OR: 2.418; 95% CI: 1.410–4.146) and patients with vitiligo. Conclusions For patients with statistically significant associated risk factors, differential diagnosis and early intervention should be performed.