Effect of vitamin E–enhanced highly cross-linked polyethylene on wear rate and particle debris in anatomic total shoulder arthroplasty: a biomechanical comparison to ultrahigh-molecular-weight polyethylene

医学 聚乙烯 复合材料 材料科学
作者
Adam Z. Khan,Michael J. Maxwell,Russell Parrott,Adam Bowler,Evan A. Glass,Douglas J. Miller,Daniel Vasconcellos,James R. Brownhill,Luke Austin,Derek J. Cuff,Anand M. Murthi,Matthew J. Smith,J. Michael Wiater,Andrew Jawa
出处
期刊:Journal of Shoulder and Elbow Surgery [Elsevier]
标识
DOI:10.1016/j.jse.2023.11.016
摘要

Background

Particle-induced osteolysis resulting from polyethylene wear remains a source of implant failure in anatomic total shoulder designs. Modern polyethylene components are irradiated in an oxygen-free environment to induce cross-linking, but reducing the resulting free radicals with melting or heat annealing can compromise the component's mechanical properties. Vitamin E has been introduced as an adjuvant to thermal treatments. Anatomic shoulder arthroplasty models with a ceramic head component have demonstrated that vitamin E–enhanced polyethylene show improved wear compared with highly cross-linked polyethylene (HXLPE). This study aimed to assess the biomechanical wear properties and particle size characteristics of a novel vitamin E–enhanced highly cross-linked polyethylene (VEXPE) glenoid compared to a conventional ultrahigh-molecular-weight polyethylene (UHMWPE) glenoid against a cobalt chromium molybdenum (CoCrMo) head component.

Methods

Biomechanical wear testing was performed to compare the VEXPE glenoid to UHMWPE glenoid with regard to pristine polyethylene wear and abrasive endurance against a polished CoCrMo alloy humeral head in an anatomic shoulder wear-simulation model. Cumulative mass loss (milligrams) was recorded, and wear rate calculated (milligrams per megacycle [Mc]). Under pristine wear conditions, particle analysis was performed, and functional biologic activity (FBA) was calculated to estimate particle debris osteolytic potential. In addition, 95% confidence intervals for all testing conditions were calculated.

Results

The average pristine wear rate was statistically significantly lower for the VEXPE glenoid compared with the HXLPE glenoid (0.81 ± 0.64 mg/Mc vs. 7.00 ± 0.45 mg/Mc) (P < .05). Under abrasive wear conditions, the VEXPE glenoid had a statistically significant lower average wear rate compared with the UHMWPE glenoid comparator device (18.93 ± 5.80 mg/Mc vs. 40.47 ± 2.63 mg/Mc) (P < .05). The VEXPE glenoid demonstrated a statistically significant improvement in FBA compared with the HXLPE glenoid (0.21 ± 0.21 vs. 1.54 ± 0.49 (P < .05).

Conclusions

A new anatomic glenoid component with VEXPE demonstrated significantly improved pristine and abrasive wear properties with lower osteolytic particle debris potential compared with a conventional UHMWPE glenoid component. Vitamin E–enhanced polyethylene shows early promise in shoulder arthroplasty components. Long-term clinical and radiographic investigation needs to be performed to verify if these biomechanical wear properties translate to diminished long-term wear, osteolysis, and loosening.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
LL完成签到,获得积分10
1秒前
ww完成签到,获得积分10
2秒前
共享精神应助DJ想吃饭了采纳,获得10
3秒前
itsserene应助科研通管家采纳,获得30
3秒前
大模型应助科研通管家采纳,获得10
3秒前
3秒前
老胡给我鼠完成签到,获得积分10
4秒前
4秒前
4秒前
Cc完成签到,获得积分10
4秒前
4秒前
不经山发布了新的文献求助30
5秒前
5秒前
6秒前
6秒前
7秒前
竹筏过海应助笨笨石头采纳,获得30
8秒前
8秒前
魏万天完成签到,获得积分10
8秒前
端庄白开水完成签到,获得积分20
8秒前
thy完成签到 ,获得积分10
8秒前
leolee完成签到 ,获得积分10
8秒前
科研达人发布了新的文献求助10
9秒前
风之旅人发布了新的文献求助10
10秒前
10秒前
dlm发布了新的文献求助10
11秒前
bastien发布了新的文献求助10
11秒前
彭于晏应助魏万天采纳,获得10
11秒前
11秒前
12秒前
12秒前
ghh发布了新的文献求助30
12秒前
12秒前
赵文斌关注了科研通微信公众号
12秒前
13秒前
kangsynat完成签到 ,获得积分10
13秒前
泡泡发布了新的文献求助10
13秒前
Neonoes完成签到 ,获得积分10
13秒前
14秒前
嘎嘎猛完成签到 ,获得积分10
15秒前
高分求助中
Evolution 10000
The Young builders of New china : the visit of the delegation of the WFDY to the Chinese People's Republic 1000
юрские динозавры восточного забайкалья 800
English Wealden Fossils 700
Foreign Policy of the French Second Empire: A Bibliography 500
Chen Hansheng: China’s Last Romantic Revolutionary 500
China's Relations With Japan 1945-83: The Role of Liao Chengzhi 400
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3147820
求助须知:如何正确求助?哪些是违规求助? 2798873
关于积分的说明 7832037
捐赠科研通 2455841
什么是DOI,文献DOI怎么找? 1306979
科研通“疑难数据库(出版商)”最低求助积分说明 627957
版权声明 601587