孟德尔随机化
医学
结直肠癌
全基因组关联研究
孟德尔遗传
遗传学
基因组
肿瘤科
癌症
生物信息学
计算生物学
单核苷酸多态性
内科学
基因
基因型
生物
遗传变异
作者
Ruhina Shirin Laskar,Conghui Qu,Jeroen R. Huyghe,Tabitha A. Harrison,Richard B. Hayes,Yin Cao,Peter T. Campbell,Robert S. Steinfelder,Fazlur Rahman Talukdar,Hermann Brenner,Shuji Ogino,S. Brendt,D. Timothy Bishop,Daniel D. Buchanan,Andrew T. Chan,Michelle Cotterchio,Stephen B. Gruber,Andrea Gsur,Bethany Van Guelpen,Mark A. Jenkins
标识
DOI：10.1016/j.annonc.2024.02.008
摘要
Our novel findings indicate inherited susceptibility to EOCRC and suggest modifiable lifestyle and metabolic targets that could also be used to risk-stratify individuals for personalized screening strategies or other interventions.
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