Trends in risk factor control and treatment among patients with non‐alcoholic fatty liver disease and type 2 diabetes between 2000 and 2020: A territory‐wide study

医学 2型糖尿病 脂肪肝 内科学 糖尿病 二甲双胍 置信区间 风险因素 胃肠病学 血压 疾病 内分泌学 胰岛素
作者
Xinrong Zhang,Terry Cheuk‐Fung Yip,Yee–Kit Tse,Vicki Wing‐Ki Hui,Guanlin Li,Huapeng Lin,Lilian Yan Liang,Jimmy Shiu Ming Lai,Mandy Sze-Man Lai,Johnny T. K. Cheung,Henry Lik‐Yuen Chan,Stephen L. Chan,Alice Pik‐Shan Kong,Grace Lai‐Hung Wong,Vincent Wai‐Sun Wong
出处
期刊:Alimentary Pharmacology & Therapeutics [Wiley]
卷期号:57 (10): 1103-1116 被引量:2
标识
DOI:10.1111/apt.17428
摘要

Summary Background & Aims We aimed to determine the trends in risk factor control and treatment among patients with non‐alcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D) in 2000–2020. Methods We conducted a territory‐wide cohort study of adult patients with NAFLD and T2D diagnosed between 1 January 2000 and 31 July 2021 in Hong Kong. T2D was defined by use of any anti‐diabetic agents, laboratory tests and/or diagnosis codes. Results This study included 16,084 patients with NAFLD and T2D (mean age, 54.8 ± 12.0 years; 7124 male [44.3%]). The percentage of patients achieving individualised haemoglobin A 1c (HbA 1c ) targets increased from 44.5% (95% confidence interval [CI], 42.9–46.1) to 64.8% (95% CI, 64.1–65.5), and percentage of patients achieving individualised low‐density lipoprotein‐cholesterol (LDL‐C) targets increased from 23.3% (95% CI, 21.9–24.7) to 54.3% (95% CI, 53.5–55.1) from 2000–2005 to 2016–2020, whereas percentage of patients achieving blood pressure control (<140/90 mm Hg) remained static at 53.1–57.2%. Combination therapy for diabetes increased, especially among those with poor glycaemic control, but there was no increase in combination therapy for hypertension. Fewer cirrhotic patients achieved blood pressure control and individualised LDL‐C targets, but they were more likely to achieve individualised HbA 1c targets than non‐cirrhotics. Metformin and statins were underused in cirrhotic patients. Younger patients (18–44 years) were less likely to achieve individualised HbA 1c targets than middle‐aged (45–64 years) and older ones (≥65 years). Conclusions From 2000 to 2020, glycaemic and lipid control improved significantly, whereas blood pressure control remained static among patients with NAFLD and T2D.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
晒黑的雪碧完成签到,获得积分10
1秒前
yao chen完成签到,获得积分10
2秒前
catch完成签到,获得积分10
2秒前
Hrx完成签到,获得积分10
2秒前
哎呀哎呀25完成签到,获得积分10
3秒前
6秒前
Shark完成签到 ,获得积分10
6秒前
我要发财完成签到,获得积分10
7秒前
卡卡罗特完成签到,获得积分10
7秒前
7秒前
天天向上完成签到 ,获得积分10
8秒前
Xinxxx完成签到,获得积分10
8秒前
Echoheart完成签到,获得积分10
8秒前
Hrx发布了新的文献求助10
9秒前
我要发财发布了新的文献求助10
11秒前
WJing发布了新的文献求助10
12秒前
haonanchen完成签到,获得积分10
13秒前
彭于晏应助专注的白柏采纳,获得10
13秒前
99v587完成签到,获得积分10
14秒前
愤怒的小马发布了新的文献求助200
15秒前
朴素海亦完成签到 ,获得积分10
16秒前
wishes完成签到 ,获得积分10
17秒前
17秒前
南城完成签到 ,获得积分10
18秒前
18秒前
20秒前
Andy完成签到,获得积分10
22秒前
伦语发布了新的文献求助10
22秒前
xdc发布了新的文献求助10
24秒前
zoe发布了新的文献求助10
26秒前
ccCherub完成签到,获得积分10
28秒前
霍楠完成签到,获得积分10
28秒前
星辰大海应助rainny采纳,获得10
28秒前
EZ完成签到 ,获得积分10
28秒前
谨慎翎完成签到 ,获得积分10
29秒前
tiantian8715完成签到,获得积分10
29秒前
如泣草芥完成签到,获得积分0
29秒前
jzhecb完成签到 ,获得积分10
30秒前
花海完成签到,获得积分10
30秒前
lingck完成签到,获得积分10
30秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Handbook of Industrial Diamonds.Vol2 1100
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038368
求助须知:如何正确求助?哪些是违规求助? 3576068
关于积分的说明 11374313
捐赠科研通 3305780
什么是DOI,文献DOI怎么找? 1819322
邀请新用户注册赠送积分活动 892672
科研通“疑难数据库(出版商)”最低求助积分说明 815029