医学
癌症
内科学
营养不良
前瞻性队列研究
肿瘤科
风险因素
系统回顾
重症监护医学
梅德林
政治学
法学
作者
Irene Lidoriki,Dimitrios Schizas,Maximos Frountzas,Nikolaos Machairas,Anastasia Prodromidou,Alkistis Kapelouzou,Ioannis Karavokyros,Emmanouil Pikoulis,Stefanos N. Kales,Theodore Liakakos
标识
DOI:10.1080/01635581.2020.1756350
摘要
Oncologic patients often suffer from malnutrition which in turn, might have negative impact on treatment outcomes. The Geriatric Nutritional Risk Index (GNRI), as an index of impaired nutritional status, has emerged as a significant prognostic factor for short-and long-term outcomes in cancer patients. The aim of the current systematic review is to determine whether the GNRI is an independent prognostic factor of postoperative complications and survival in cancer patients. A systematic search was conducted to identify studies, published from 2005 to 2019, which assessed associations between GNRI and short- and long-term outcomes in cancer patients. Eighteen studies fulfilled the eligibility criteria and were included in the analysis. Low scores of GNRI were associated with increased risk for developing postoperative complications and impaired survival of cancer patients in most studies. Our findings support the use of the GNRI in the clinical practice, since it is a simple and reliable tool for assessing nutritional status in oncologic patients. More prospective, multi-centered studies are warranted to confirm the current results, as well as the role of nutritional support in improving the prognosis of cancer patients.
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