A near-infrared fluorescent probe for hydrogen polysulfides detection with a large Stokes shift

Due to the crucial biological roles of hydrogen polysulfides (H2Sn) in living systems, the selective determination of H2Sn is essential. In this work, we reported a turn-on fluorescent probe, JSI-Sn, for H2Sn with high sensitivity and good selectivity. Probe JSI-Sn displayed a near-infrared emission (λmaxEm = 701 nm) and a large Stokes shift (123 nm) in the presence of H2Sn in solution. Using probe JSI-Sn as an indispensable tool, the monitoring of intracellular H2Sn in living cells and zebrafish were realized.