医学
亚临床感染
活检
肾移植
移植
炎症
内科学
胃肠病学
病理
标识
DOI:10.1016/j.kint.2020.04.052
摘要
Borderline T cell–mediated rejection is a diagnostic category of the Banff schema that uses a lower diagnostic threshold. Subclinical borderline T cell–mediated rejection detected by surveillance sampling is not entirely benign. Studies demonstrate increased rates of late rejection, progressive nephron loss, functional impairment, donor-specific antibody formation, and allograft failure. It can be conceptualized as a failure to control the cellular alloimmune response. Mixed results are reported for its treatment, and randomized controlled trials are needed.
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