西洛他唑
医学
磷酸二酯酶
血管舒张
机制(生物学)
血管扩张剂
磷酸二酯酶3
药理学
磷酸二酯酶抑制剂
血小板聚集
心脏病学
血小板聚集抑制剂
血小板
内科学
化学
阿司匹林
哲学
酶
认识论
生物化学
作者
Huilei Zheng,Hua Yang,Danping Gong,Lanxian Mai,Xiaoling Qiu,Lidai Chen,Xiaozhou Su,Ruoqi Wei,Zhiyu Zeng
标识
DOI:10.2174/1568026619666191122123855
摘要
: Cilostazol is a unique platelet inhibitor that has been used clinically for more than 20 years. As a phosphodiesterase type III inhibitor, cilostazol is capable of reversible inhibition of platelet aggregation and vasodilation, has antiproliferative effects, and is widely used in the treatment of peripheral arterial disease, cerebrovascular disease, percutaneous coronary intervention, etc. This article briefly reviews the pharmacological mechanisms and clinical application of cilostazol.
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