清晨好,您是今天最早来到科研通的研友!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您科研之路漫漫前行!

Chemoradiotherapy in Cancer Treatment: Rationale and Clinical Applications.

癌症 临床试验 结直肠癌
作者
Kathrine S Rallis,Thomas Ho Lai Yau,Michail Sideris
出处
期刊:Anticancer Research [International Institute of Anticancer Research (IIAR) Conferences 1997. Athens, Greece. Abstracts]
卷期号:41 (1): 1-7 被引量:6
标识
DOI:10.21873/anticanres.14746
摘要

Chemoradiotherapy (CRT) refers to the combined administration of both chemotherapy and radiotherapy as an anticancer treatment. Over the years, CRT has become an established treatment for a diverse range of locally advanced solid tumours. The rationale for CRT is based on the two concepts of spatial cooperation and in-field cooperation, whereby the end goal is to achieve synergistic antitumour effects from the combination of both treatment modalities. CRT offers notable patient survival benefits and local disease control without significant long-term toxicities. Although the enhancement of cytotoxic effects inevitably increases damage to normal tissues as well as tumour cells, if the damage to normal tissue is lesser than that to tumour cells, CRT is still deemed beneficial. Thus, the search to optimise dose, timings and fractionation of CRT is of particular interest. Considering the recent success achieved with anticancer immunotherapies including immune checkpoint inhibitors, the combination of CRT and immunotherapy has emerged as an exciting field of research with the potential for significant clinical benefit. This report outlines the rationale underlying CRT and discusses its advantages through clinical examples focusing on anal, cervical, non-small-cell lung cancer and bladder cancer.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
辣酒猫完成签到,获得积分20
30秒前
辣酒猫发布了新的文献求助10
35秒前
37秒前
周周南完成签到 ,获得积分10
43秒前
56秒前
59秒前
533发布了新的文献求助10
1分钟前
稻子完成签到 ,获得积分10
1分钟前
梨子茶发布了新的文献求助30
1分钟前
领导范儿应助Huck采纳,获得10
1分钟前
1分钟前
Huck发布了新的文献求助10
1分钟前
Huck完成签到,获得积分10
1分钟前
整齐的蜻蜓完成签到 ,获得积分10
1分钟前
1分钟前
zhang完成签到,获得积分10
1分钟前
2分钟前
小余同学发布了新的文献求助10
2分钟前
coolplex完成签到 ,获得积分10
2分钟前
2分钟前
2分钟前
lenny发布了新的文献求助10
2分钟前
迷茫的一代完成签到,获得积分10
2分钟前
可爱沛蓝完成签到 ,获得积分10
2分钟前
大模型应助科研通管家采纳,获得10
2分钟前
lenny完成签到,获得积分10
2分钟前
方白秋完成签到,获得积分10
3分钟前
3分钟前
Betty发布了新的文献求助10
3分钟前
4分钟前
丘比特应助过氧化氢采纳,获得30
4分钟前
fufufu123完成签到 ,获得积分10
4分钟前
幽默的忆霜完成签到 ,获得积分10
4分钟前
健壮保温杯完成签到,获得积分10
4分钟前
4分钟前
4分钟前
4分钟前
小糊涂完成签到 ,获得积分10
4分钟前
5分钟前
vbnn完成签到 ,获得积分10
5分钟前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 1000
Immigrant Incorporation in East Asian Democracies 600
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
A Preliminary Study on Correlation Between Independent Components of Facial Thermal Images and Subjective Assessment of Chronic Stress 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3968504
求助须知:如何正确求助?哪些是违规求助? 3513331
关于积分的说明 11167297
捐赠科研通 3248697
什么是DOI,文献DOI怎么找? 1794417
邀请新用户注册赠送积分活动 875030
科研通“疑难数据库(出版商)”最低求助积分说明 804652