生物利用度
黄酮醇
多酚
黄酮类
类黄酮
化学
食品科学
花青素
异黄酮素
抗氧化剂
生物化学
药理学
生物
色谱法
作者
Chiara Di Lorenzo,Francesca Colombo,Simone Biella,Creina S. Stockley,Patrizia Restani
出处
期刊:Nutrients
[MDPI AG]
日期:2021-01-19
卷期号:13 (1): 273-273
被引量:501
摘要
Polyphenols are a group of phytochemicals with potential health-promoting effects. They are classified as flavonoid (flavonols, flavanols, flavones, flavanones, isoflavones, and anthocyanins) and non-flavonoid molecules (phenolic acids, hydroxycinnamic acids, lignans, stilbenes, and tannins). Although an increasing number of trials have shown a correlation among polyphenol consumption and a reduction in risk factors for chronic diseases, discrepancies in explaining their positive effects have been found in terms of the bioavailability. In fact, polyphenols show a low bioavailability due to several factors: interaction with the food matrix, the metabolic processes mediated by the liver (phase I and II metabolism), intestine and microbiota. On the other hand, the biological activities of phenol compounds may be mediated by their metabolites, which are produced in vivo, and recent studies have confirmed that these molecules may have antioxidant and anti-phlogistic properties. This review discusses the studies performed in vivo, which consider the polyphenol bioavailability and their different food sources. Factors influencing the biological effects of the main classes of polyphenols are also considered.
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