限制
医学
药品
药物输送
癌症
癌症治疗
纳米技术
药理学
重症监护医学
内科学
材料科学
工程类
机械工程
作者
С. Г. Клочков,Маргарита Е. Неганова,Vladimir N. Nikolenko,Kuo Chen,Siva G. Somasundaram,Cecil E. Kirkland,Gjumrakch Aliev
标识
DOI:10.1016/j.semcancer.2019.08.028
摘要
The use of nanoparticles dramatically increases the safety and efficacy of the most common anticancer drugs. The main advantages of nano-drugs and delivery systems based on nano-technology are effective targeting, delayed release, increased half-life, and less systemic toxicity. The use of nano-carriers has led to significant improvements in drug delivery to targets compared with traditional administration of these drugs. In this review, the main tendencies in nano-drug formulations as well as factors limiting their use in clinical settings are discussed. Additionally, the current status of approved nano-drugs for cancer treatment is reviewed.
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