大疱性类天疱疮
天疱疮
类天疱疮
医学
寻常性天疱疮
自身抗体
皮肤病科
桥粒胶蛋白3
免疫学
抗体
作者
Hossein C. Nousari,Grant J. Anhalt
出处
期刊：The Lancet
[Elsevier]
日期：1999-08-01
卷期号：354 (9179): 667-672
被引量：192
标识
DOI：10.1016/s0140-6736(99)03007-x
摘要
Pemphigus and bullous pemphigoid are distinct autoimmune blistering diseases that are characterised by the presence of autoantibodies directed against specific adhesion molecules of the skin and mucous membranes. The comparison and contrast of molecular mechanism of blister formation of these two diseases provide a rational diagnostic and therapeutic approach to affected patients. Pemphigus and bullous pemphigoid are distinct autoimmune blistering diseases that are characterised by the presence of autoantibodies directed against specific adhesion molecules of the skin and mucous membranes. The comparison and contrast of molecular mechanism of blister formation of these two diseases provide a rational diagnostic and therapeutic approach to affected patients.
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