Single-Compound Libraries of Organic Materials: Parallel Synthesis and Screening of Fluorescent Dyes

“Hits” with high quantum yields: The screening of the chromophores of a coumarin library for optical properties allowed the identification of “hits” with high fluorescence quantum yields (see picture) which could be used as fluorescence labels and laser dyes. The generation of the library was facilitated by an efficient method involving the parallel synthesis utilizing Pd-catalyzed cross-coupling reactions.