Use of 1,1,1,3,3,3-hexamethyldisilazane and N,O-bis-(trimethylsilyl)acetamide in aromatic Claisen rearrangement: An efficient method for preventing abnormal Claisen rearrangement

Both 1,1,1,3,3,3-hexamethyldisilazane and N,O-bis-(trimethylsilyl)acetamide have been shown to suppress the formation of abnormal aromatic Claisen rearrangement products by efficiently trapping the incipient normal products as their silyl ethers under mild conditions.