Association between long-term exposure to air pollution and mortality in France: A 25-year follow-up study

危险系数 四分位间距 比例危险模型 医学 队列 人口学 空气污染 队列研究 环境卫生 置信区间 化学 内科学 有机化学 社会学
作者
Malek Bentayeb,Vérène Wagner,Morgane Stempfelet,Marie Zins,Marcel Goldberg,Mathilde Pascal,Sophie Larrieu,Pascal Beaudeau,Sylvie Cassadou,Daniel Eilstein,Laurent Filleul,Alain Le Tertre,Sylvia Médina,Laurence Pascal,Hélène Prouvost,Philippe Quénel,Abdelkrim Zeghnoun,Agnès Lefranc
出处
期刊:Environment International [Elsevier BV]
卷期号:85: 5-14 被引量:99
标识
DOI:10.1016/j.envint.2015.08.006
摘要

Long-term exposure to air pollution (AP) has been shown to have an impact on mortality in numerous countries, but since 2005 no data exists for France.We analyzed the association between long-term exposure to air pollution and mortality at the individual level in a large French cohort followed from 1989 to 2013.The study sample consisted of 20,327 adults working at the French national electricity and gas company EDF-GDF. Annual exposure to PM10, PM10–2.5, PM2.5, NO2, O3, SO2, and benzene was assessed for the place of residence of participants using a chemistry-transport model and taking residential history into account. Hazard ratios were estimated using a Cox proportional-hazards regression model, adjusted for selected individual and contextual risk factors. Hazard ratios were computed for an interquartile range (IQR) increase in air pollutant concentrations.The cohort recorded 1967 non-accidental deaths. Long-term exposures to b aseline PM2.5, PM10-25, NO2 and benzene were associated with an increase in non-accidental mortality (Hazard Ratio, HR = 1.09; 95% CI: 0.99, 1.20 per 5.9 μg/m3, PM10-25; HR=1.09; 95% CI: 1.04, 1.15 per 2.2 μg/m3, NO2: HR=1.14; 95% CI: 0.99, 1.31 per 19.3 μg/m3 and benzene: HR=1.10; 95% CI: 1.00, 1.22 per 1.7 μg/m3).The strongest association was found for PM10: HR = 1.14; 95% CI: 1.05, 1.25 per 7.8 μg/m3. PM10, PM10-25 and SO2 were associated with non-accidental mortality when using time varying exposure. No significant associations were observed between air pollution and cardiovascular and respiratory mortality.Long-term exposure to fine particles, nitrogen dioxide, sulfur dioxide and benzene is associated with an increased risk of non-accidental mortality in France. Our results strengthen existing evidence that outdoor air pollution is a significant environmental risk factor for mortality. Due to the limited sample size and the nature of our study (occupational), further investigations are needed in France with a larger representative population sample.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
Ava应助oui采纳,获得10
刚刚
能干的吐司完成签到,获得积分10
1秒前
1秒前
jjjdcjcj发布了新的文献求助10
1秒前
周破儿完成签到,获得积分10
1秒前
量子星尘发布了新的文献求助10
1秒前
传奇3应助明朗采纳,获得10
2秒前
2秒前
2秒前
3秒前
senhoo发布了新的文献求助10
3秒前
3秒前
小狗完成签到 ,获得积分10
4秒前
5秒前
5秒前
昏睡的实验室小白完成签到,获得积分10
6秒前
6秒前
yar应助大青山采纳,获得10
6秒前
Rondab应助mariawang采纳,获得10
6秒前
yqb发布了新的文献求助10
6秒前
6秒前
一条裸游的鱼完成签到,获得积分10
8秒前
二白关注了科研通微信公众号
8秒前
9秒前
9秒前
超帅听枫发布了新的文献求助10
9秒前
11秒前
11秒前
fish1116发布了新的文献求助100
11秒前
11秒前
bbbbb沫完成签到,获得积分20
11秒前
峥2发布了新的文献求助10
11秒前
wzy完成签到,获得积分10
11秒前
xxxllllll发布了新的文献求助10
12秒前
干净映天完成签到 ,获得积分10
12秒前
LJ_scholar发布了新的文献求助10
13秒前
kuny完成签到,获得积分10
13秒前
勤恳的夏之完成签到,获得积分20
14秒前
wzy发布了新的文献求助10
14秒前
钵钵鸡完成签到 ,获得积分10
14秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3988732
求助须知:如何正确求助?哪些是违规求助? 3531027
关于积分的说明 11252281
捐赠科研通 3269732
什么是DOI,文献DOI怎么找? 1804764
邀请新用户注册赠送积分活动 881869
科研通“疑难数据库(出版商)”最低求助积分说明 809021