Association between long-term exposure to air pollution and mortality in France: A 25-year follow-up study

危险系数 四分位间距 比例危险模型 医学 队列 人口学 空气污染 队列研究 环境卫生 置信区间 化学 内科学 有机化学 社会学
作者
Malek Bentayeb,Vérène Wagner,Morgane Stempfelet,Marie Zins,Marcel Goldberg,Mathilde Pascal,Sophie Larrieu,Pascal Beaudeau,Sylvie Cassadou,Daniel Eilstein,Laurent Filleul,Alain Le Tertre,Sylvia Médina,Laurence Pascal,Hélène Prouvost,Philippe Quénel,Abdelkrim Zeghnoun,Agnès Lefranc
出处
期刊:Environment International [Elsevier BV]
卷期号:85: 5-14 被引量:99
标识
DOI:10.1016/j.envint.2015.08.006
摘要

Long-term exposure to air pollution (AP) has been shown to have an impact on mortality in numerous countries, but since 2005 no data exists for France.We analyzed the association between long-term exposure to air pollution and mortality at the individual level in a large French cohort followed from 1989 to 2013.The study sample consisted of 20,327 adults working at the French national electricity and gas company EDF-GDF. Annual exposure to PM10, PM10–2.5, PM2.5, NO2, O3, SO2, and benzene was assessed for the place of residence of participants using a chemistry-transport model and taking residential history into account. Hazard ratios were estimated using a Cox proportional-hazards regression model, adjusted for selected individual and contextual risk factors. Hazard ratios were computed for an interquartile range (IQR) increase in air pollutant concentrations.The cohort recorded 1967 non-accidental deaths. Long-term exposures to b aseline PM2.5, PM10-25, NO2 and benzene were associated with an increase in non-accidental mortality (Hazard Ratio, HR = 1.09; 95% CI: 0.99, 1.20 per 5.9 μg/m3, PM10-25; HR=1.09; 95% CI: 1.04, 1.15 per 2.2 μg/m3, NO2: HR=1.14; 95% CI: 0.99, 1.31 per 19.3 μg/m3 and benzene: HR=1.10; 95% CI: 1.00, 1.22 per 1.7 μg/m3).The strongest association was found for PM10: HR = 1.14; 95% CI: 1.05, 1.25 per 7.8 μg/m3. PM10, PM10-25 and SO2 were associated with non-accidental mortality when using time varying exposure. No significant associations were observed between air pollution and cardiovascular and respiratory mortality.Long-term exposure to fine particles, nitrogen dioxide, sulfur dioxide and benzene is associated with an increased risk of non-accidental mortality in France. Our results strengthen existing evidence that outdoor air pollution is a significant environmental risk factor for mortality. Due to the limited sample size and the nature of our study (occupational), further investigations are needed in France with a larger representative population sample.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
SciGPT应助魏源采纳,获得10
4秒前
暴躁小龙完成签到,获得积分10
4秒前
5秒前
大模型应助勤奋梨愁采纳,获得10
5秒前
zwk完成签到,获得积分10
6秒前
Meidina完成签到,获得积分10
6秒前
微醺小王完成签到,获得积分10
7秒前
8秒前
David发布了新的文献求助20
10秒前
gan完成签到,获得积分10
10秒前
Jasper应助nini采纳,获得10
10秒前
暴躁小龙发布了新的文献求助10
10秒前
量子星尘发布了新的文献求助10
10秒前
遇见完成签到 ,获得积分10
12秒前
12秒前
只想困瞌睡完成签到,获得积分10
13秒前
tonyhuang完成签到,获得积分10
13秒前
鸣蜩阿六完成签到,获得积分10
15秒前
笃定完成签到,获得积分10
15秒前
41应助潘善若采纳,获得10
15秒前
15秒前
18秒前
momo发布了新的文献求助10
18秒前
whisper完成签到,获得积分10
19秒前
momo应助奚斌采纳,获得10
20秒前
情怀应助十九岁的时差采纳,获得10
21秒前
独角兽完成签到 ,获得积分10
22秒前
zhy完成签到,获得积分10
22秒前
22秒前
Rondab应助bluebear采纳,获得10
23秒前
David完成签到,获得积分10
27秒前
文档发布了新的文献求助10
27秒前
付创发布了新的文献求助10
27秒前
ssw完成签到,获得积分10
27秒前
大白发布了新的文献求助10
30秒前
MHM完成签到,获得积分10
32秒前
首席或雪月完成签到,获得积分10
33秒前
天天快乐应助用户5063899采纳,获得10
33秒前
36秒前
Oxygen完成签到,获得积分10
37秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989297
求助须知:如何正确求助?哪些是违规求助? 3531418
关于积分的说明 11253893
捐赠科研通 3270097
什么是DOI,文献DOI怎么找? 1804884
邀请新用户注册赠送积分活动 882087
科研通“疑难数据库(出版商)”最低求助积分说明 809158