A Review of Exercise-Based Rehabilitation Strategies in Patients with Myocardial Infarction: Focus on High-Intensity Interval Training

Background and Aim : Despite progressive improvement in medical therapy and standard care, Exercisebased rehabilitation programs have been shown to to have beneficial cardiovascular effects in patients with myocardial infarction through a multifactorial effect. This review study aimed to evaluate exercise-based cardiac rehabilitation strategies in patients with myocardial infarction with special focus on high intensity interval training, as a growing field of research was conducted. Material and Methods: This is a systematic review study on articles published, without limitation Year, by searching in reputable databases such as PabMed, Science Direct, Google Scholar, Scopus, Springer. Also in the process of searching for articles on the keywords microRNAs (miRNA) and myocardial infarction "," cardiac rehabilitation and myocardial infarction "," cardiac rehabilitation and high-intensity interval training (HIIT) ", high-intensity interval training (HIIT) and Myocardial infarction was used. Ethical considerations: All Ethical principles in writing this article have been observed according to the instructions of the National Ethics Committee and the COPE regulations. Results: High-intensity interval training (HIIT) is a safe and effective exercise strategy to improve cardiac function in MI, and to prevent abnormal changes in mass, size, geometry, and cardiac function after MI, and Applies significant changes in molecular targets and cell pathway. Conclusion: Therefore, HIIT targets myocardial necroptosis due to oxidative stress, protects the heart against adverse left ventricular regeneration after MI, and can be considered an integral part of post-MI cardiac rehabilitation programs.