In this work, silicone rubber based on conductive polymer composites containing carbon nanotubes (CNTs) and synergetic reduced graphene oxide (rGO) was used to fabricate highly elastic sensors through a simple strategy. Notably, the porosity of the sensor is tunable by incorporating the different sized inorganic salt particles. The porosity and filler conductive networks significantly influenced the sensing performance of the sensor. Benefiting from the controllable porosity and synergistic effect, the sensor exhibits a high conductivity of 2.8 × 10−4 (S/m), high strain sensitivity (0–2.5%, GF = 14.18; 21–35%, GF = 13.1), high pressure sensitivity (0–2.5%, S = 3.4 kPa−1; 2.5–6.3%, S = 0.26 kPa−1; 6.3–12%, S = 0.03 kPa−1), high linearity (R2 > 0.97), fast response (∼97 ms), and good repeatability (1000 cycles). Based on these good sensing performances, the sensor is applied to detect both physiological activities (the pulse signal from arteries) and movements of the human body (bending of fingers, arms and knees), measure pressure distribution and identify temperature.