PD-1+ Tcf1+ CD8+ T cells from established chronic infection can form memory while retaining a stable imprint of persistent antigen exposure

(Cell Reports 36, 109672-1–109672-14.e1–e4; September 7, 2021) In the originally published version of this article, the title contained a typo, where “stable imprint” was inadvertently changed to one word during the production process. The title has now been corrected online. The production team regrets this error. PD-1+ Tcf1+ CD8+ T cells from established chronic infection can form memory while retaining a stable imprint of persistent antigen exposureCharmoy et al.Cell ReportsSeptember 07, 2021In BriefAlthough memory-like PD-1+ Tcf1+ CD8+ T cells (TMLs) sustain the immune response to chronic viral infection, the fate of these cells in the absence of persistent stimulation has remained unclear. Charmoy et al. find that TMLs can yield functional memory that retains a permanent imprint of prior chronic stimulation. Full-Text PDF Open Access