Synthesis and characterization of a stable and inert MnII-based ZnII responsive MRI probe for molecular imaging of glucose stimulated zinc secretion (GSZS)

A Zn II responsive Mn II -based MRI contrast agent, [Mn(PC2A-DPA)], has been synthesized, investigated and applied in imaging studies. It shows high stability and excellent inertness and can be used to visualize glucose triggered Zn II release by MRI.