亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Blink reflex: A practical test to evaluate the trigeminal nerve injury following percutaneous balloon compression for the treatment of trigeminal neuralgia

三叉神经痛 医学 角膜反射 三叉神经 麻醉 经皮 外科 神经痛 反射 气球 前瞻性队列研究 置信区间 内科学 神经病理性疼痛
作者
Chengwen Ma,Fuyu Tian,Le Zhou,Jianying Gu,Zhang Xi,Junjie Quan,Jianqiang Qu,Xianxia Yan
出处
期刊:Headache [Wiley]
卷期号:62 (3): 363-373 被引量:1
标识
DOI:10.1111/head.14269
摘要

To evaluate the blink reflex (BR) in estimating the potential injury of trigeminal nerve following percutaneous balloon compression (PBC) surgery, and to determine the association between BR alterations and early surgical outcomes.In this single-center, prospective before-and-after study, a total of 74 patients who had primary trigeminal neuralgia and scheduled for PBC between October 2020 and June 2021 were prospectively included. BR testing and facial sensory assessment were performed pre- and post-PBC. The latency and the area under the curve (AUC) of pre- and postoperative R1 (R1pre /R1post ) and R2 (R2pre /R2post ) were measured.The BR components were noticeably delayed or diminished following PBC. R1post was elicited in only 26 patients, and absent in 48 patients. The residual R1post had markedly reduced AUC (median difference [Hodges-Lehmann]: -59.5, 95% confidence interval [CI]: -217.5 to -6.9, p = 0.023). Compared with R2pre , the latency of R2post was considerably delayed (mean difference: 4.3, 95% CI: 2.9 to 5.7, p < 0.001) and the AUC was greatly suppressed (median difference [Hodges-Lehmann]: -388.4, 95% CI: -548.4 to -259.5, p < 0.001). After PBC, 58 patients had immediate total pain relief, and 16 had partial relief. The absence of R1post was found in 46 of 58 (79.3%) patients with complete remission, whereas in only 2 of 16 (12.5%) patients with partial relief. Association analysis showed that the absence of R1post was strongly associated with total pain relief (46/58 [79.3%] vs. 2/16 [12.5%], odds ratio [OR]: 26.8, 95% CI: 5.4 to 134.5, Cramér's V: 0.6, p < 0.001). The latency of R2post in patients with total relief was significantly delayed (mean difference: 2.5, 95% CI: 0.3 to 4.6, p = 0.028). Patients experienced graded facial numbness after PBC, of whom 31 reported mild numbness (Grades I-II) and 43 reported more severe numbness (Grades III-IV). The absence of R1post was significantly associated with facial numbness severity, 33/43 (76.7%) in Grades III-IV vs. 15/31 (48.4%) in Grades I-II (OR: 0.284, 95% CI: 0.105 to 0.771, Cramér's V: 0.3, p = 0.012). In patients with more severe numbness, the latency of R2post was significantly delayed (mean difference: 2.7, 95% CI: 0.1 to 5.3, p = 0.043), and the reduction of AUC was much greater (median difference [Hodges-Lehmann]: 17.2, 95% CI: 0.5 to 35.4, p = 0.041).Both R1 and R2 were significantly diminished after PBC and these alterations were associated with early surgical outcomes, suggesting that the BR is useful in evaluating trigeminal injury following PBC and could provide objective information about early prognosis.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
CNY完成签到 ,获得积分10
3秒前
赘婿应助_ban采纳,获得10
28秒前
38秒前
bksqc发布了新的文献求助10
41秒前
bksqc完成签到,获得积分10
48秒前
卑微学术人完成签到 ,获得积分10
1分钟前
1分钟前
无花果应助feifei采纳,获得10
1分钟前
griffon完成签到,获得积分10
1分钟前
汉堡包应助通通采纳,获得10
1分钟前
1分钟前
Huay完成签到 ,获得积分10
1分钟前
tingting9发布了新的文献求助10
1分钟前
英俊的铭应助科研通管家采纳,获得10
1分钟前
1分钟前
kd1412应助科研通管家采纳,获得10
1分钟前
善学以致用应助吴昕昕采纳,获得10
1分钟前
tingting9完成签到,获得积分10
1分钟前
吾日三省吾身完成签到,获得积分10
2分钟前
sola完成签到 ,获得积分10
2分钟前
DreamMaker完成签到 ,获得积分10
2分钟前
VVV完成签到,获得积分10
2分钟前
2分钟前
2分钟前
_ban发布了新的文献求助10
2分钟前
小黄鸭完成签到,获得积分10
2分钟前
滴滴哒发布了新的文献求助10
2分钟前
李李原上草完成签到 ,获得积分10
2分钟前
超级的千青完成签到 ,获得积分10
2分钟前
2分钟前
Bio应助又来注水了采纳,获得30
3分钟前
万能图书馆应助爹爹采纳,获得10
3分钟前
layman完成签到,获得积分10
3分钟前
郭郭完成签到 ,获得积分10
3分钟前
FL完成签到 ,获得积分10
3分钟前
科研通AI5应助sljzhangbiao11采纳,获得10
3分钟前
又来注水了完成签到,获得积分10
3分钟前
快乐海豚完成签到 ,获得积分10
3分钟前
科研通AI5应助科研通管家采纳,获得10
3分钟前
科研狗的春天完成签到 ,获得积分10
3分钟前
高分求助中
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3990020
求助须知:如何正确求助?哪些是违规求助? 3532077
关于积分的说明 11256276
捐赠科研通 3270943
什么是DOI,文献DOI怎么找? 1805139
邀请新用户注册赠送积分活动 882270
科研通“疑难数据库(出版商)”最低求助积分说明 809228