耐辐射球菌
脱球菌
舍瓦内拉
锰
细菌
微生物学
化学
电离辐射
细胞内
恶臭假单胞菌
希瓦氏菌属
生物
放射化学
辐照
生物化学
遗传学
物理
有机化学
核物理学
作者
Michael J. Daly,Elena K. Gaidamakova,Vera Y. Matrosova,А. Т. Василенко,Min Zhai,Amudhan Venkateswaran,Matthias Hess,Marina V. Omelchenko,Heather M. Kostandarithes,Kira S. Makarova,Lawrence P. Wackett,James K. Fredrickson,Debabrota Ghosal
出处
期刊:Science
[American Association for the Advancement of Science (AAAS)]
日期:2004-11-05
卷期号:306 (5698): 1025-1028
被引量:574
标识
DOI:10.1126/science.1103185
摘要
Deinococcus radiodurans is extremely resistant to ionizing radiation. How this bacterium can grow under chronic gamma radiation [50 grays (Gy) per hour] or recover from acute doses greater than 10 kGy is unknown. We show that D. radiodurans accumulates very high intracellular manganese and low iron levels compared with radiation-sensitive bacteria and that resistance exhibits a concentration-dependent response to manganous chloride [Mn(II)]. Among the most radiation-resistant bacterial groups reported, Deinococcus, Enterococcus, Lactobacillus, and cyanobacteria accumulate Mn(II). In contrast, Shewanella oneidensis and Pseudomonas putida have high iron but low intracellular manganese concentrations and are very sensitive. We propose that Mn(II) accumulation facilitates recovery from radiation injury.
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